Updated Jan. 10, 2026, 9:48 p.m. PT
The Philadelphia Eagles are the favorites, but by less than a touchdown (-6), in this season’s Wild Card Round of the NFC playoffs, where they will oppose the San Francisco 49ers. Lincoln Financial Field in Philadelphia, Pennsylvania will act as host on January 11, 2026, starting at 4:30 p.m. ETand airing on FOX. The over/under in the contest is set at 44.5 points.
The 49ers lost versus the Seattle Seahawks in their last game, 13-3.
In that game against the Seahawks, Niners quarterback Brock Purdy completed 19 of 27 passes for 127 yards, with no touchdowns and one interception.
The Eagles lost versus the Washington Commanders in their last game, 24-17.
49ers vs Eagles betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 12:48 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Expert NFL picks: Exclusive betting insights only at USA TODAY.Spread favorite: Philadelphia (-6)Moneyline: Philadelphia (-272), San Francisco (+221)Total: 44.5 points49ers betting insightsThis year away from home, San Francisco is 7-2 against the spread and 7-2 overall.The 49ers have registered an 11-6-0 record against the spread this season.San Francisco is unbeaten ATS (1-0) as 6-point underdogs or more on the road.The 49ers are a perfect 1-0 ATS when playing as at least 6-point underdogs.This season, in nine road games, San Francisco has gone over the total six times.49ers games have finished with a final combined score above the over/under 10 times this season.49ers leadersPurdy: 2,167 PASS YDS / 240.8 YPG / 69.4% / 20 TD / 10 INT / 33 CAR / 147 RUSH YDS / 3 TDChristian McCaffrey: 311 CAR / 1,202 YDS / 70.7 YPG / 10 TD / 102 REC / 924 YDS / 54.4 YPG / 7 TDBrian Robinson Jr.: 92 CAR / 400 YDS / 23.5 YPG / 2 TD / 8 REC / 25 YDS / 1.5 YPG / 0 TDJauan Jennings: 55 REC / 643 YDS / 42.9 YPG / 9 TDGeorge Kittle: 57 REC / 628 YDS / 57.1 YPG / 7 TD49ers vs Eagles game infoDate: Sunday, January 11, 2026Time: 4:30 p.m. ETCity: Philadelphia, PennsylvaniaVenue: Lincoln Financial FieldTV channel: FOXLive stream: Watch on Fubo (Regional restrictions may apply)Watch Philadelphia Eagles vs. San Francisco 49ers on Fubo! (Regional restrictions may apply)
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