FRESNO, Calif. (FOX26) — Firefighters were called out to a vacant house fire again on Tuesday morning.

It started around 4:30 a.m. at a boarded-up structure on the 1800 block of East Olive Avenue, a house they have been to at least 11 times.

While approaching, they could see a large column of smoke from far away and requested additional resources.

Crews take defensive approach as fire destroy familiar vacant house in Fresno (Courtesy: Fresno Fire)

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When they arrived, crews found heavy smoke and flames coming from the vacant residence.

Due to the intense fire and significant structural damage from multiple prior fires, firefighters were forced to take a defensive stance on the outside.

A total of 32 firefighters worked to put out the fire. The structure was deemed a total loss.

There were no injuries.

The cause of the fire remains unknown, but the property is known for homeless activity.