The San Francisco Giants head south to take on their division rival San Diego Padres tonight at Petco Park.

Taking the mound for the Giants will be right-hander Landen Roupp, who completed the 2025 season with a 3.80 ERA, 3.91 FIP with 102 strikeouts to 45 walks in 106.2 innings pitched.

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He’ll be facing off against Padres right-hander Walker Buehler, who completed the 2025 season with a 4.93 ERA, 5.66 FIP with 92 strikeouts to 61 walk in 126 innings pitched between the Boston Red Sox and Philadelphia Phillies. Buehler, of course, is a familiar face in the NL West, having played the majority of his career thus far with the Los Angeles Dodgers.

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Game #4

Who: San Francisco Giants (0-3) vs. San Diego Padres (1-2)

Where: Petco Park, San Diego, California

When: 6:40 p.m. PT

Regional broadcast: NBC Sports Bay Area

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National broadcast: Fox Sports 1

Radio: KNBR 680 AM/104.5 FM, KSFN 1510 AM