49ers vs. Giants injury report

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Apr 26, 2025; San Francisco, California, USA; San Francisco 49ers running back Christian McCaffrey (center) sits courtside during the third quarter of game three of first round between the Golden State Warriors and the Houston Rockets for the 2024 NBA Playoffs at Chase Center.

The San Francisco 49ers (5-3) have 19 players on the injury report, including Mac Jones, ahead of their matchup versus the New York Giants (2-6) at MetLife Stadium, on Sunday, Nov. 2 at 1 p.m. ET.

Watch San Francisco 49ers vs. New York Giants on Fubo! (Regional restrictions may apply)49ers vs Giants TV channel & game infoGame day: Sunday, November 2, 2025Game time: 1 p.m. ETLocation: East Rutherford, New JerseyStadium: MetLife StadiumTV channel: CBSLive stream: Watch on Fubo! (Regional restrictions may apply)Live stream: Watch on Paramount+! (Regional restrictions may apply)Watch San Francisco 49ers vs. New York Giants on Fubo! (Regional restrictions may apply)Need a news break? Check out the all new PLAY hub with puzzles, games and more!49ers injury reportBryce Huff | DL (Out)Injury: HamstringPractice Status: Did Not Participate In Practice2025 Defensive Stats: 4.0 Sacks | 6.0 Tackles for Loss | 19 Tackles | 0 Interceptions | 1 Pass DefendedYetur Gross-Matos | DL (Out)Injury: KneePractice Status: Did Not Participate In PracticeRicky Pearsall | WR (Out)Injury: KneePractice Status: Did Not Participate In Practice2025 Receiving Stats: 29 Targets | 20 Receptions | 327 Yards | 0 TouchdownsJake Brendel | OL (Out)Injury: HamstringPractice Status: Did Not Participate In Practice2025 Season Stats: 3 Games PlayedBen Bartch | OL (Questionable)Injury: AnklePractice Status: Limited Participation in Practice2024 Season Stats: 1 Game PlayedJordan Elliott | DL (Questionable)Injury: AnklePractice Status: Did Not Participate In Practice2025 Defensive Stats: 0.0 Sacks | 1.0 Tackles for Loss | 16 Tackles | 0 Interceptions | 0 Passes DefendedSam Okuayinonu | DL (Questionable)Injury: AnklePractice Status: Limited Participation in Practice2025 Defensive Stats: 1.0 Sack | 2.0 Tackles for Loss | 21 Tackles | 0 Interceptions | 0 Passes DefendedSpencer Burford | OL (Questionable)Injury: KneePractice Status: Full Participation in PracticeBrock Purdy | QB (Questionable)Injury: ToePractice Status: Limited Participation in Practice2025 Passing: 73-for-48 | 586 Yards | 4 Touchdowns | 4 InterceptionsDee Winters | LB (Questionable)Injury: KneePractice Status: Limited Participation in Practice2025 Defensive Stats: 0.0 Sacks | 4.0 Tackles for Loss | 54 Tackles | 0 Interceptions | 3 Passes DefendedChristian McCaffrey | RBInjury: RestPractice Status: Full Participation in Practice2025 Rushing: 140 Attempts | 490 Yards | 3 Touchdowns2025 Receiving Stats: 74 Targets | 56 Receptions | 559 Yards | 3 TouchdownsUpton Stout | CBInjury: ShoulderPractice Status: Full Participation in Practice2025 Defensive Stats: 1.0 Sack | 2.0 Tackles for Loss | 34 Tackles | 0 Interceptions | 2 Passes DefendedJauan Jennings | WRInjury: AnklePractice Status: Full Participation in Practice2025 Receiving Stats: 36 Targets | 18 Receptions | 212 Yards | 1 TouchdownGeorge Kittle | TEInjury: ObliquePractice Status: Full Participation in PracticeAlfred Collins | DTInjury: ShoulderPractice Status: Full Participation in PracticeKalia Davis | DLInjury: HandPractice Status: Full Participation in PracticeKeion White | DLInjury: Nir – otherPractice Status: Limited Participation in PracticeTrent Williams | OTInjury: RestPractice Status: Full Participation in Practice2025 Season Stats: 3 Games PlayedMac Jones | QBInjury: KneePractice Status: Full Participation in Practice2025 Passing: 226-for-149 | 1,597 Yards | 8 Touchdowns | 5 Interceptions49ers insightsThe 49ers have put up fewer points per game over their past three matchups (18.0) than they have averaged for the season (20.0).Turning our attention to yardage, San Francisco has amassed fewer total yards per game over its previous three matchups (303.3) than it has averaged for the season (348.6).In the passing game, the 49ers have racked up fewer passing yards per game over their previous three matchups (207.0) than they have averaged for the season (259.3).San Francisco has piled up slightly more rushing yards per game over its last three matchups (96.3) than it has averaged for the season (89.4).49ers vs Giants odds

NFL odds courtesy of BetMGM. Odds updated Saturday at 5:30 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread Favorite: 49ers (-2.5)Moneyline: 49ers (-145), Giants (+122)Total: 48.5 pointsWatch San Francisco 49ers vs. New York Giants on Fubo! (Regional restrictions may apply)

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