San Francisco’s June election carries high stakes for Mayor Daniel Lurie, with two key allies on the Board of Supervisors facing voters for the first time after being appointed to their seats. The outcome could reshape City Hall and affect his ability to execute his agenda. Meanwhile, voters will weigh in on Propositions C and D — dueling measures that could change how the city taxes big businesses. Lurie opposes both measures. And, for the first time in nearly 4 decades, voters are faced with an open congressional seat with the imminent departure of Speaker Emerita Nancy Pelosi.