The San Francisco 49ers opened their 2026 NFL season with a commanding 27-7 win over the Los Angeles Rams in Melbourne, Australia, on Thursday even – or Friday morning local time.

The NFC West rivals usually put together a competitive showing against each other, but head coach Kyle Shanahan had his team ready from the start. Quarterback Brock Purdy looked in mid-season form, throwing for 205 yards with three touchdowns and an interception.

The offense appeared out of synch all day for quarterback Matthew Stafford and head coach Sean McVay, being held to just seven points. Stafford struggled, throwing for only 155 yards and an interception.

Here are the highlights from Thursday night’s game.

Sep 10, 2026 – 7:30p ET

Final Score

Live Coverage for this has ended

Sep 10, 2026 – 11:18p ET

Stetson Bennett Enters The Game For Matthew Stafford; Rams Starters Pulled

Sep 10, 2026 – 11:05p ET

49ers Extend Lead To 20 Points After Eddy Pineiro’s 56-Yard Field Goal

Sep 10, 2026 – 11:00p ET

Fred Warner Forced Fumble Keeps 49ers In Front With Commanding Lead

Sep 10, 2026 – 10:56p ET

49ers, Rams Play In Front Of Historic Crowd In Melbourne

Sep 10, 2026 – 10:48p ET

49ers Finish 99-Yard Drive With Deebo Samuel Touchdown

Sep 10, 2026 – 10:38p ET

49ers Defense Denies Matthew Stafford At The Goal Line

Sep 10, 2026 – 10:25p ET

Mike Evans Scores His First 49ers Touchdown

Sep 10, 2026 – 9:56p ET

De’Zhaun Stribling Ruled Out With Ankle Injury

Sep 10, 2026 – 9:39p ET

Brock Purdy Connects With DeMarcus Robinson For 38-Yard Touchdown

Sep 10, 2026 – 9:35p ET

De’Zhaun Stribling Leaves Game With Lower Leg Injury

Sep 10, 2026 – 9:29p ET

Renardo Green Picks Off Matthew Stafford

Sep 10, 2026 – 9:23p ET

Quentin Lake Intercepts Brock Purdy

Sep 10, 2026 – 9:18p ET

Matthew Stafford Connects With Puka Nacua For Big Gain

Sep 10, 2026 – 9:15p ET

Kyren Williams Scores Five-Yard Rushing Touchdown

Sep 10, 2026 – 8:53p ET

49ers Strike First With Eddy Pineiro Field Goal

Sep 10, 2026 – 8:22p ET

Myles Garrett Set To Make His Rams Debut

Sep 10, 2026 – 7:57p ET

Sights & Sounds At Melbourne Cricket Ground

Sep 10, 2026 – 7:31p ET

Inactives For 49ers-Rams

Live Coverage for this began on Sep 10, 2026 – 11:31p ET