The second day of the draft will begin with the San Francisco 49ers … we think.

General manager John Lynch said there are a handful of players the team already has circled for pick No. 33. Then again, he knows other teams around the league will regroup this morning and perhaps make the 49ers, who traded down twice on Thursday, yet another offer.

“We’re always open for business,” Lynch said with a smile.

The 49ers, who had just one Day 2 pick when the draft began, now have three — Nos. 33 and 58 in the second round and No. 90 in the third round. Here are the prospects who could tempt them …

Day 2Denzel Boston, WR, Washington

Boston was the top-ranked receiver to fall out of Round 1 in this talented class, and a 6-4 touchdown scorer with elite ball skills might be hard for the 49ers to pass up. He could help out on third downs and in the red zone while he learns how the big guys do it from Mike Evans.

Cashius Howell, edge, Texas A&M

Howell seems like nearly a perfect prospect for San Francisco — a fast, versatile edge player who was productive in the SEC. Ah, but his arms are historically short for a first-round defensive lineman, raising the question of whether he’ll get engulfed by longer, stronger NFL offensive linemen. His arms scared off any Round 1 suitors. Will they scare off the 49ers in Round 2?

T.J. Parker, edge, Clemson

Parker has a nice mix of power and speed and can also rush the passer from inside. He is coming off a disappointing 2025 season but had a very strong showing at the Senior Bowl.

Emmanuel McNeil-Warren, S, Toledo

Would the 49ers draft a safety this high? It would break precedent, but the draft board — and McNeil-Warren’s skill set — could force the issue. He’s a tall, fluid, physical safety who covers tight ends and forces fumbles, eight of them in the past three seasons.

Zion Young, edge, Missouri

The 49ers did most of their pre-draft work on fleet-footed edge players. Young is a little different in that he’s nearly 6-6 and 265 pounds and doesn’t offer much value in coverage. Still, he finished with 16 1/2 tackles for loss last year and would be a natural bookend to Nick Bosa.

R Mason Thomas, edge, Oklahoma

Thomas doesn’t have the measurables, but he has a lot of film of getting to the quarterback. He has a great first step and never stops going, and the 49ers could do worse.

Germie Bernard, WR, Alabama

He doesn’t have the speed of some of the other receivers in this draft, but Bernard can line up anywhere and separate underneath. He is tough and likes to get dirty blocking in the run game, which assuredly made the 49ers smile during the scouting process.

Chris Bell, WR, Louisville

Bell is a big-bodied receiver with excellent hands and impressive acceleration. His biggest downside: He had surgery for a torn ACL in December, and it’s unclear when he’ll resume practicing. That would make for a difficult start under a head coach in Kyle Shanahan who is notoriously demanding when it comes to rookie receivers.

Keyron Crawford, edge, Auburn

Crawford’s another player who’s equally comfortable dropping into coverage or rushing the passer. Teams might be wary that he has just one season as an SEC starter. That also could mean, however, that he has more room to grow.

Caleb Tiernan, T, Northwestern

Tiernan, a longtime starter at left tackle for the Wildcats, falls into an intriguing category for the 49ers: someone who could begin at guard and move to tackle when there’s an opening. He’s also been durable in the rough-and-tumble Big Ten, starting all 38 games over the past three seasons.

Gabe Jacas, edge, Illinois

When we asked readers for their mock drafts, Jacas was a popular second-round pick, but it’s hard to see the 49ers drafting a poor man’s Mykel Williams a year after taking the original.

Christen Miller, DT, Georgia

The 49ers traded for Osa Odighizuwa and drafted Alfred Collins and CJ West last year, but Miller might be too long and too quick to pass up if he’s still there at No. 58.

Emmanuel Pregnon, G, Oregon

The second round is probably too early for the 49ers to draft a guard. Then again, Pregnon checks a lot of boxes for size, length and the fact he’s well-versed at left guard, an open spot for the 49ers.

Chase Bisontis, G, Texas A&M

Bisontis, who was also a left guard in college, is better than Pregnon at the zone-blocking techniques the 49ers run. His shorter arms, however, give him issues in pass protection, and he might ultimately be best at center, which could be a 49ers need next season when Jake Brendel’s contract expires.

Jaishawn Barham, edge, Michigan

Barham is someone you’d rarely have to take off the field. He’s accustomed to being an off-the-ball linebacker, though his physical profile — 6-3, 240 pounds, with violent hands — suggests he’d also hold up well as a pass rusher.

Derrick Moore, edge, Michigan

Moore has good technique and is the better player right now, but Michigan teammate Barham has more twitch and explosiveness and has the higher ceiling.

Eli Stowers, TE, Vanderbilt

A former quarterback, Stowers had 386 yards after the catch last season and then had a 45.5-inch vertical jump at the NFL Scouting Combine.

Dani Dennis-Sutton, edge, Penn State

A tall, long-limbed edge rusher who had 8.5 sacks in each of the past two seasons at Penn State, Dennis-Sutton also had three forced fumbles and three pass defenses in 2025.

Malachi Fields, WR, Notre Dame

He doesn’t have the wiggle Shanahan prefers, but Fields has terrific size and body control, and he’s a load to bring down. He might be a good successor to Jauan Jennings as the team’s “power slot” receiver.

A.J. Haulcy, S, LSU

Haulcy has the size (215 pounds) of a strong safety and the downfield instincts of a free safety. He has eight interceptions over the past two seasons (five at Houston, three at LSU)

Chris Brazzell II, WR, Tennessee

At 6-4, Brazzell is just the sort of tall, swivel-hipped wideout Shanahan has liked in the past, and the team brought him in on an official visit. Brazzell, however, is rail thin, didn’t have to deal with much press coverage in college and did not distinguish himself — at all — as a blocker.

Skyler Bell, WR, UConn

Bell doesn’t have impressive size (5-11, 192), but he had more than 800 yards after the catch last season, which speaks to his toughness and determination. He also showed he could handle a demanding workload: He was targeted 141 times last season.

Domonique Orange, DT, Iowa State

Nicknamed “Big Citrus,” the 322-pound Orange doesn’t offer much as a pass rusher but is considered one of the better run-game disrupters in the draft. Would the 49ers be interested? Defensive line coach Kris Kocurek reportedly attended his pro day at Iowa State.

De’Zhaun Stribling, WR, Ole Miss

Stribling is one of the more willing blockers at wideout in this draft, which will no doubt catch the eyes of Shanahan and receivers coach Leonard Hankerson. He also had six touchdowns and more than 800 receiving yards in each of the past two seasons.

Sam Roush, TE, Stanford

A polished blocker who needs work on his route running, Roush is the opposite of most of the Day 2 tight ends.

Antonio Williams, WR, Clemson

Williams is the type of fluid route runner Shanahan has liked in the past (see: Ricky Pearsall, Jordan Watkins). That he returns punts is a noteworthy bonus.

Brandon Cisse, CB, South Carolina

It’s hard to see the Niners taking a cornerback in the second round, but Cisse sees the field well, can cover and has elite closing speed.

Gennings Dunker, G, Iowa

Dunker did not give up a sack at right tackle last season, but scouts see his future inside at guard. He’s strong as an ox with a mullet, and the 49ers’ offensive line coach, Chris Foerster, loves the Iowa program and the players it cranks out.

Elijah Sarratt, WR, Indiana

Nicknamed “Waffle House” because he is always open, Sarratt used his size and body control to make tough catches when he wasn’t. He could be there on Day 3, because he doesn’t have elite speed or loose hips.

Tyler Onyedim, DT, Texas A&M

Onyedim was one of the players the 49ers hosted at team headquarters earlier this month. He’s had good length, including 34 1/4-inch arms, and is the type of one-gap penetrator the team looks for on the defensive line.

Zachariah Branch, WR, Georgia

Branch was arrested Sunday morning for obstructing a police officer, so we’ll see if that knocks him out of Day 2. Cliff Branch’s great-nephew is an explosive slot receiver and punt returner who will be somewhat of a project because Georgia never had him do much besides catch quick hitters.

Ted Hurst, WR, Georgia State

A popular sleeper pick, the long-legged 6-4 speedster had a limited route tree in college and has average hands. There will be a huge leap in the quality of cornerbacks he is going against, but some teams are excited about the potential.

Day 3Jude Bowry, T, Boston College

Bowry has good size for the position — 6-5 with nearly 11-inch hands — and he’s played right and left tackle. He’s a bit of a late bloomer, which might make him a solid Day 3 pick who could marinate a year or two behind Williams.

Brian Parker II, G/C, Duke

Parker played right tackle for the Blue Devils, but he has a background at center. He could compete at center and guard for the 49ers early in his career and move into a starting center role should the team move on from Brendel next year.

Dametrious Crownover, T, Texas A&M

At 6-7 with nearly 36-inch arms, Crownover jumps out for his length, and he held up well against top-notch talent at the Senior Bowl. He’d be a developmental prospect, especially at left tackle, but his natural gifts might make him a project worth pursuing.

VJ Payne, S, Kansas State

The poor man’s Nick Emmanwori — hey, use some imagination — would join former Wildcat teammate Marques Sigle in what should be a spirited competition with Malik Mustapha and Ji’Ayir Brown.

Chris McClellan, DT, Missouri

A big-bodied defender with 11-inch mitts that our Dane Brugler described as “bear-claw hands.”

Nate Boerkircher, TE, Texas A&M

Boerkircher is a good-sized (6-5) tight end who, after five seasons at Nebraska, showed at Texas A&M that he was capable as a pass catcher. He’d give the 49ers another inline blocker with some receiving ability.

Bryce Lance, WR, North Dakota State

In 2021, Lynch joked he would keep an eye on Trey Lance’s little brother, a high schooler at the time. Is he still interested? Bryce Lance ran a 4.34-second 40 at the combine and averaged more than 21 yards per catch last season. He’d be a solution to the 49ers’ inability to stretch the field in recent seasons.

Oscar Delp, TE, Georgia

Delp bears a resemblance to former Georgia tight end Charlie Woerner, whom the 49ers drafted in the sixth round in 2020. Both can play all over the formation, including in the backfield. It’s worth noting Lynch traveled to Athens, Ga., last month for the Bulldogs’ pro day.

Deion Burks, WR, Oklahoma

At 5-10, 180 pounds, Burks definitely is on the small side for an NFL player. Still, his contact balance and effectiveness on jet sweeps show skills that have interested Shanahan in the past. Burks seems like the type of player the 49ers might take in the late fourth round.

Gracen Halton, DT, Oklahoma

The 49ers are always looking for explosive interior defensive linemen. That’s Halton, who clocked a 4.82-second 40 at 292 pounds and was a fan favorite at Oklahoma for his energetic play style. He’d certainly be a culture fit for Kocurek.

Jalen Farmer, G, Kentucky

Farmer has excellent size and length, including 34 1/4-inch arms. Though he’s played mostly right guard in a power-blocking scheme, his athleticism suggests someone who could master zone-blocking concepts.

Rayshaun Benny, DT, Michigan

Benny has the type of quick first step the 49ers look for. His lack of production — just three tackles for loss in 13 starts last season — will likely make him a Day 3 pick.

Michael Trigg, TE, Baylor

Trigg doesn’t stand out as a blocker, and he has trouble catching in traffic, flaws that likely will make him a Day 3 pick. But he can also make circus catches downfield and is very tough to bring down when he has the ball in his hands. Shanahan has used a tight end as his “power slot” in the past, and Trigg might be a good fit in that role.

Kage Casey, G, Boise State

The 6-6, 310-pound Casey was a three-year starter at left tackle but might project as a guard or even a center.

Ja’Kobi Lane, WR, USC

Lane made some wizard-like catches at USC, and his 6-4 height makes him a red zone threat. He doesn’t offer much burst, however, and didn’t do much after the catch for the Trojans, which likely makes him a mid-Day 3 selection.

Alex Harkey, G, Oregon

A right tackle for the Ducks, Harkey projects to guard in the NFL. The 49ers liked him enough to invite him for a formal visit earlier this month.

Eli Heidenreich, RB/WR, Navy

Heidenreich is one of the few running backs in the draft with receiver-like qualities, which ought to appeal to Shanahan. His level of competition in college was suspect, though he held up very well at the East-West Shrine Bowl in January.