The San Francisco Giants host the San Diego Padres for the first time this season, looking to end a six-game losing streak on Monday.

The San Diego Padres look to catapult themselves into first place in the National League West standings when they travel to take on the San Francisco Giants on Monday night for the first game of this rivalry series. The Padres are just 0.5 games back of the Los Angeles Dodgers and look to turn the page on back-to-back series losses in Chicago against the Cubs and White Sox. San Diego prevailed against the White Sox on Sunday to avoid a sweep and ended a four-game losing streak. The Giants haven’t been as fortunate coming off back-to-back sweeps against the Philadelphia Phillies and Tampa Bay Rays. San Francisco has lost six games in a row and is in last place in the NL West with a 13-21 record. The Giants are 7-9 at home, while the Padres are 20-13 overall and 9-5 on the road. San Francisco leads the season series against San Diego, beating the Padres 2-1 on the road in the first series.

How to Watch San Diego Padres vs San Francisco Giants Today:

Game Date: Monday, May 4, 2026

Game Time: 9:45 p.m. ET

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TV Channel: San Diego Padres (NEW), MLB.TV – San Diego Padres

Location: Oracle Stadium – San Francisco, CA

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The Rays completed the series sweep against the Giants on Sunday in a 2-1 final in 10 innings. Jonathan Aranda had a walkoff RBI single to go 4-for-5 on the day. The Giants scored the first run of the game on an RBI single from designated hitter Casey Schmitt in the first inning, driving in Rafael Devers. San Francisco was not able to score again thought, with Tampa Bay tying the game in the bottom of the eighth on a sac bunt. The offense wasn’t able to back up a good start from Tyler Mahle, who went 5.1 scoreless innings while giving up only four hits and striking out five. San Francisco has yet to announce who they will be starting in this opener against the Padres.

The Padres avoided a sweep at the hands of the White Sox on Sunday, also in a one-run game, winning 4-3. Xander Bogaerts played the hero, driving in the go-ahead run on a single in the eighth. Miguel Andujar and Manny Machado hit solo shots in the fourth inning to help San Diego end its four-game losing streak. Chicago tied the game in the seventh on a two-run shot from Derek Hill to wipe out a solid start from Griffin Canning, who gave up one run in five innings on three hits. The Padres will start Randy Vasquez, who is trying to stay perfect on the season. The righty is 3-0 with a 2.94 ERA in 33.2 innings pitched.

What Time Is The San Diego Padres vs San Francisco Giants Game On?

The San Diego Padres vs San Francisco Giants game will take place on Monday, May 4, 2026 at 9:45 p.m. ET. Tune in and catch all the MLB action.

What Channel Is The San Diego Padres vs San Francisco Giants On?

Looking to watch this game? Fans can tune into San Diego Padres (NEW), MLB.TV – San Diego Padres to see the action. Make sure you subscribe to Fubo now to watch this match and many other baseball games.

Live stream San Diego Padres vs San Francisco Giants on Fubo: Start Watching Today!

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