The crash happened around 1:12 a.m. on southbound Interstate 5 near Washington Street, according to the California Highway Patrol.
Investigators said an Infiniti carrying two women crashed into the center divider for unknown reasons before coming to a stop in traffic lanes. Both occupants got out of the car before a Toyota SUV driven by a 52-year-old Chula Vista man struck the disabled vehicle and the 20-year-old passenger of the Infiniti.