UC San Francisco news release

A new study helps explain why people with HIV remain at elevated risk for type 2 diabetes despite effective suppression of the virus with modern medications.

To investigate it, the team compared blood samples and fat biopsies from 46 people living with well-controlled HIV to those from 74 people without HIV. None of the participants were obese or had diabetes.

The researchers found that the people with HIV had more fibrosis, or scarring, in their fat tissues, and this was associated with insulin resistance — a key predictor of type 2 diabetes. This fibrosis was obvious in HIV patients no matter their body weight or the specific kinds of HIV medications they were taking.

Read the full news release here.