(FOX40.COM) — One person is dead and two others were injured after a vehicle crashed into a tree Wednesday night in Sacramento County, the California Highway Patrol said.

The crash occurred at about 4:16 p.m. on Business 80 near Watt Avenue. The vehicle struck a tree, seriously injuring the driver and two passengers, CHP said.

All three occupants were taken to a local hospital with major injuries. The driver was pronounced dead at the hospital, CHP said.

A CHP spokesperson told FOX40 the collision appears to be the result of a medical emergency, and neither alcohol nor drugs are suspected to be factors in the crash.