{"id":172371,"date":"2026-02-10T20:50:06","date_gmt":"2026-02-10T20:50:06","guid":{"rendered":"https:\/\/www.newsbeep.com\/us-ca\/172371\/"},"modified":"2026-02-10T20:50:06","modified_gmt":"2026-02-10T20:50:06","slug":"2026-mti-parkinsons-therapeutics-awardees-announced","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us-ca\/172371\/","title":{"rendered":"2026 MTI Parkinson\u2019s Therapeutics Awardees Announced"},"content":{"rendered":"<p><img decoding=\"async\" alt=\"headshots of the awardees\" src=\"https:\/\/www.newsbeep.com\/us-ca\/wp-content\/uploads\/2026\/02\/mti_parkinsons_awardees_2026.jpg\"\/><\/p>\n<p>Parkinson\u2019s disease afflicts more than ten million people worldwide, and with prevalence continuing to rise, the need for therapies that do more than merely mask symptoms has become urgent. In response, UC Berkeley\u2019s <a href=\"https:\/\/moleculartherapeutics.org\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Molecular Therapeutics Initiative (MTI)<\/a> has selected three research teams for the inaugural <a href=\"https:\/\/moleculartherapeutics.org\/mti-launches-parkinsons-therapeutics-program-invites-proposals\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">MTI Parkinson\u2019s Therapeutics Program<\/a>, launched last autumn to transform high-impact academic discoveries into therapeutic leads. These awards were made possible through a generous philanthropic gift that enables MTI to pursue bold, high-risk strategies with the potential for transformative clinical impact.<\/p>\n<p>The 2026 awardees are <a href=\"https:\/\/mcb.berkeley.edu\/faculty\/bbs\/wilsonr\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Ross Wilson<\/a> and <a href=\"https:\/\/innovativegenomics.org\/ctg\/advanced-translational-genetics-laboratory\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Hanqin Li<\/a> of the <a href=\"https:\/\/innovativegenomics.org\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Innovative Genomics Institute<\/a>, <a href=\"https:\/\/chemistry.berkeley.edu\/people\/markita-landry\" rel=\"nofollow noopener\" target=\"_blank\">Markita Landry<\/a> and <a href=\"https:\/\/vcresearch.berkeley.edu\/faculty\/stephan-lammel\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Stephan Lammel<\/a> from the <a href=\"https:\/\/chemistry.berkeley.edu\/home\" rel=\"nofollow noopener\" target=\"_blank\">College of Chemistry<\/a> and <a href=\"https:\/\/neuroscience.berkeley.edu\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Department of Neuroscience<\/a>, and <a href=\"https:\/\/vcresearch.berkeley.edu\/faculty\/eunyong-park\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Eunyong Park<\/a> with graduate researcher <a href=\"https:\/\/parklab.mcb.berkeley.edu\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Laurie Wang<\/a> in <a href=\"https:\/\/mcb.berkeley.edu\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Molecular &amp; Cell Biology<\/a>. Each team receives $90,000 in seed funding and priority access to MTI\u2019s drug discovery capabilities, and medicinal-chemistry platforms, resources that allow projects to advance through pre-clinical milestones fast. The proposal review panel featured leading Parkinson\u2019s experts, including Nobel laureate <a href=\"https:\/\/vcresearch.berkeley.edu\/faculty\/randy-schekman\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Randy Schekman<\/a>, scientific chair of the <a href=\"https:\/\/parkinsonsroadmap.org\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Aligning Science Across Parkinson\u2019s (ASAP) initiative<\/a>, and <a href=\"https:\/\/www.michaeljfox.org\/bio\/patrik-brundin-md-phd\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Dr. Patrik Brundin<\/a>, Therapeutic Area Leader for Movement Disorders at <a href=\"https:\/\/www.roche.com\/stories\/redefining-parkinson-s-disease\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Roche<\/a> and an executive scientific advisor of the <a href=\"https:\/\/www.michaeljfox.org\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Michael J. Fox Foundation<\/a>.<\/p>\n<p>MTI accelerates high-risk, cutting-edge academic research toward viable therapeutic applications for Parkinson\u2019s disease. Wilson and Li will refine a genome-editing strategy that gently lowers production of \u03b1-synuclein, the protein whose misfolded aggregates seed Lewy bodies, aiming to intervene before toxic clumps form. Landry and Lammel will combine regenerative transcription factors with near-infrared nanosensors to rebuild dopamine circuitry and measure neurotransmission in real time, shifting the paradigm beyond dopamine replacement toward circuit restoration. Park and Wang will search for small molecules that enhance protein-mediated mitophagy, opening a pharmacological route to preserve mitochondrial quality control, a central safeguard against neurodegeneration.<\/p>\n<p>By converging on protein toxicity, circuitry failure, and mitochondrial dysfunction, the three projects are aimed at slowing or halting Parkinson\u2019s progression rather than masking tremor and rigidity. MTI\u2019s integrated translational ecosystem provides the infrastructure these ideas need to mature quickly, bridging discovery science with drug development, and positioning <a href=\"https:\/\/www.berkeley.edu\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">UC Berkeley<\/a> researchers to make a meaningful impact on a disorder whose burden is growing faster than any other major neurological disease.<\/p>\n","protected":false},"excerpt":{"rendered":"Parkinson\u2019s disease afflicts more than ten million people worldwide, and with prevalence continuing to rise, the need for&hellip;\n","protected":false},"author":2,"featured_media":172372,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[143,145,144],"class_list":{"0":"post-172371","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-oakland","8":"tag-oakland","9":"tag-oakland-headlines","10":"tag-oakland-news"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts\/172371","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/comments?post=172371"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts\/172371\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/media\/172372"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/media?parent=172371"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/categories?post=172371"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/tags?post=172371"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}