{"id":199799,"date":"2026-03-01T23:26:26","date_gmt":"2026-03-01T23:26:26","guid":{"rendered":"https:\/\/www.newsbeep.com\/us-ca\/199799\/"},"modified":"2026-03-01T23:26:26","modified_gmt":"2026-03-01T23:26:26","slug":"high-prevention-efficacy-and-breakthrough-infections-on-lenacapavir-for-prep","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us-ca\/199799\/","title":{"rendered":"High prevention efficacy and \u201cbreakthrough infections\u201d on lenacapavir for PrEP"},"content":{"rendered":"<p>San Francisco AIDS Foundation news story<\/p>\n<p>\u201cBreakthrough\u201d HIV infections among people receiving long-acting injectable lenacapavir for PrEP in two major clinical trials were a topic of discussion at CROI 2026.<\/p>\n<p>Across two large clinical trials testing long-acting lenacapavir for PrEP, with thousands of cisgender women, men who have sex with men, and gender diverse people who have sex with men, a total of four individuals seroconverted during the study period while receiving on-time medication injections.<\/p>\n<p>Why did lenacapavir fail to protect a small number of people from acquiring HIV in the study?, questioned one clinician from the University of Colorado during the presentation\u2019s Q&amp;A. \u201cI think patients want to know, and I think we need that information soon. I\u2019ve already had someone who declined to use lenacapavir because of the breakthrough infections.\u201d<\/p>\n<p>Read the full news story <a href=\"https:\/\/www.sfaf.org\/collections\/beta\/new-research-high-prevention-efficacy-and-breakthrough-infections-on-lenacapavir-for-prep\/\" target=\"_blank\" rel=\"noopener nofollow\">here<\/a>.<\/p>\n<p>\u00a0<\/p>\n<p>Source : <a href=\"https:\/\/www.sfaf.org\/collections\/beta\/new-research-high-prevention-efficacy-and-breakthrough-infections-on-lenacapavir-for-prep\/\" target=\"_blank\" rel=\"nofollow noopener\">San Francisco AIDS Foundation<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"San Francisco AIDS Foundation news story \u201cBreakthrough\u201d HIV infections among people receiving long-acting injectable lenacapavir for PrEP in&hellip;\n","protected":false},"author":2,"featured_media":199800,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[101,103,102,104,106,105],"class_list":{"0":"post-199799","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-san-francisco","8":"tag-san-francisco","9":"tag-san-francisco-headlines","10":"tag-san-francisco-news","11":"tag-sf","12":"tag-sf-headlines","13":"tag-sf-news"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts\/199799","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/comments?post=199799"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts\/199799\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/media\/199800"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/media?parent=199799"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/categories?post=199799"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/tags?post=199799"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}