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Gladstone is currently recruiting lab leaders from around the world. That\u2019s despite two major challenges in the past year: the Trump administration\u2019s hostility to foreign immigration and widespread federal research cuts.<\/p>\n
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Around $80 million of Gladstone\u2019s $125 million annual budget comes from grants from the National Institutes of Health, and funding dropped by 10% last year, Srivastava said.<\/p>\n
\u201cIn the U.S. we\u2019ve really benefited from the most brilliant minds coming here. That\u2019s certainly under threat,\u201d he said.<\/p>\n
Despite the obstacles, Gladstone is continuing its expansion plans, in part by seeking more philanthropy support. Starting in 2024, Gladstone sought to raise $350 million by 2029. Around $200 million has been raised to date.<\/p>\n
Major donors include real estate developer and former Giants owners Bob Lurie and his wife Connie; real estate developer John Sobrato and his wife Susan; former venture capitalist Bill Younger, who is chair of Gladstone\u2019s board, and his wife Brenda; and hedge fund manager William Fisher, who is the son of Gap\u2019s co-founders, and his wife Sakurako; and the Dolby family.<\/p>\n
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An architect\u2019s rendering of Gladstone Institutes\u2019 new facility at 1450 Owens St. in San Francisco.<\/p>\n
DGA<\/p>\n
\u201cThe work we\u2019re doing is too important to slow at this moment when we have greater opportunity (through technology). I just wasn\u2019t willing to slow down,\u201d Srivastava said. \u201cEvery day we go slower is more people dying.\u201d<\/p>\n
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Gladstone was established in 1979 and is named for Jack David Gladstone, a real estate developer who left most of his fortune to biomedical research. The nonprofit was one of the first tenants in Mission Bay in 2004, alongside UCSF.<\/p>\n
\u201cWhen I moved here, it was all abandoned warehouses. There was just two buildings. This growth is phenomenal,\u201d Srivastava said.<\/p>\n
Alexandria Real Estate Equities, a major biotech landlord, has also built numerous Mission Bay buildings including 1450 Owens St., which marks the last major parcel in the area.<\/p>\n
Alexandria doesn\u2019t typically start construction on new buildings until it secures an anchor tenant, but did so at 1450 Owens after requests from the city, said Joel Marcus, Alexandria\u2019s executive chairman. Construction started in 2022 and was completed in 2024. (Gladstone will build its own tenant improvements and plans to move in by early 2027.)<\/p>\n
Marcus called the building \u201ca great place for innovative research,\u201d with state-of-the-art lab space.<\/p>\n
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Around half of the building remains vacant, and Marcus said both biotech and AI tenants have shown interest in the remaining space. He called Mission Bay a \u201cthriving metropolis\u201d that now has biotech, AI, housing and a major sports and entertainment complex in Chase Center.\u00a0<\/p>\n
Still, the biotech industry remains in a downturn, with widespread layoffs and funding cuts.<\/p>\n
Though Gladstone is a nonprofit, it partners with for-profit companies to take drugs through clinical trials and eventual Food and Drug Administration approval.<\/p>\n
Srivastava is \u201cstarting to see the green shoots of a resurgence,\u201d with more drug approval activity and investments.<\/p>\n
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\u201cIt\u2019s been a rough period,\u201d he said. \u201cPeople are starting to see the convergence of AI and biotech is so powerful right now.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"Gladstone Institutes has leased 105,000 square feet at 1450 Owens St. in San Francisco. Alexandria Real Estate Equities…\n","protected":false},"author":2,"featured_media":235731,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[2007,3010,1570,143,145,144,388,101,645,995],"class_list":["post-235730","post","type-post","status-publish","format-standard","has-post-thumbnail","category-oakland","tag-ai","tag-commercial-real-estate","tag-health","tag-oakland","tag-oakland-headlines","tag-oakland-news","tag-real-estate","tag-san-francisco","tag-science","tag-tech"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts\/235730","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/comments?post=235730"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts\/235730\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/media\/235731"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/media?parent=235730"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/categories?post=235730"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/tags?post=235730"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}