May 11, 2026, 2:49 p.m. ET<\/p>\n
The San Francisco Giants<\/a> (16-24) and the Los Angeles Dodgers<\/a> (24-16) open a 4-game series Monday at Dodger Stadium in Los Angeles, California. First pitch is scheduled for 10:10 p.m. ET. Let’s analyze MLB odds around the Giants vs. Dodgers odds and make our expert MLB picks and predictions<\/a> for the best bets.<\/p>\n Season series: Giants lead 2-1<\/p>\n The Giants picked up a 7-6 win Sunday against the Pittsburgh Pirates<\/a> as moderate favorites (-124) as the Over (8) cashed, clinching the series 2-1. SS Willy Adames went 3 for 4 with a double and 2 RBIs, while LF Heliot Ramos went 2 for 6 with a double, home run, 3 runs scored and 2 RBIs.<\/p>\n The Dodgers suffered a 7-2 loss Sunday against the Atlanta Braves as moderate favorites (-136), their second straight setback by that score. 3B Max Muncy had the big blow, smacking his 10th HR, while finishing with 2 RBIs. The Under (9.5) cashed in the series finale, and it has alternated with the Over in each of the past 7 games since May 3.<\/p>\n These teams met at Oracle Park in San Francisco April 21-23, and each of the games had 4 or fewer runs scored, with an average of just 3.4 combined runs per game in the series. The Under easily cashed in all 3 meetings, with the Giants winning 2 of them.<\/p>\n Watch MLB on Fubo!<\/a>Giants at Dodgers projected starters<\/p>\n RHP Trevor McDonald vs. RHP Roki Sasaki<\/p>\n McDonald (1-0, 1.29 ERA) will make his second start of 2026 and his sixth career appearance. He has a 0.29 WHIP, 0.0 BB\/9 and 10.3 K\/9 in 7 innings.<\/p>\n First start: Win, 7 IP, 1 ER, 2 H (1 solo HR), 0 BB, 8 K in 3-2 home victory vs. San Diego Padres last Monday2025 away splits (1 start, 2 appearances): 0-0, 3.38 ERA (8 IP, 3 ER), 0 HR, 2 BB, 4 KCareer vs. Dodgers (1 start): No-decision, 6 IP, 1 ER, 6 H, 1 BB, 3 K in 3-1 road victory Sept. 21, 2025<\/p>\n Sasaki (1-3, 5.97 ERA) will make his seventh start of 2026. He has a 1.67 WHIP, 4.7 BB\/9 and 8.2 K\/9 in 28 2\/3 innings.<\/p>\n Last start: Loss, 6 IP, 3 ER, 5 H (1 HR), 2 BB, 4 K in 3-2 road loss vs. St. Louis Cardinals May 22026 home splits (3 starts): 1-2, 4.85 ERA (13 IP, 7 ER), 4 HR, 8 BB, 15 K, 1.85 WHIPHas never faced GiantsGiants at Dodgers odds<\/p>\n Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub<\/a> for a full list. Lines last updated at 2:37 p.m. ET.<\/p>\n Moneyline (ML): Giants +150 (bet $100 to win $150) | Dodgers -185 (bet $185 to win $100)Run line (RL)\/Against the spread (ATS): Giants +1.5 (-140) | Dodgers -1.5 (+115)Over\/Under (O\/U): 9 (O: -110 | U: -110)<\/p>\n Slide into: BaseballHQ.com<\/a> for your fantasy baseball news. For decades, BHQ has been helping players just like you win! BHQ offers full-season subscriptions. Sign up today<\/a>!<\/p>\n Giants at Dodgers picks and predictionsPrediction<\/p>\n Giants 5, Dodgers 3<\/p>\n The GIANTS (+150) are worth a look in this series opener as moderate underdogs behind McDonald.<\/p>\n San Francisco won 2 low-scoring games in a 3-game set, and we’re picking against Sasaki here, even though the game is in Los Angeles. He has been rather shaky this season.<\/p>\n BACKING GIANTS +1.5 (-140) isn’t a bad play if you’re a bit more on the conservative side, and you just can’t bring yourself to back San Francisco straight up.<\/p>\n The Dodgers can’t be trusted to win by multiple runs, as Sasaski has been giving, and L.A. lost 2 of 3 low-scoring games against the Giants in the first go-around.<\/p>\n UNDER 9 (-110) is the lean, but go with a half-unit play at best.<\/p>\n While Sasaki has been giving, these teams combined for just 10 total runs in a 3-game set 3 weeks ago. The Under is 4-1 in the past 5 games at home for the Dodgers, too. The Over-Under is 3-3 in Sasaki’s 6 outings this season.<\/p>\n For the Giants, the Over cashed in the final 2 games of the Pirates series at home over the weekend, but the Under is 6-3 in the past 9 outings, and 8-4 across the previous 12 contests.<\/p>\n Betting odds calculator<\/a><\/p>\n .<\/p>\n For more sports betting picks and tips, check out SportsbookWire.com<\/a> and BetFTW<\/a>.<\/p>\n Follow @danieledobish<\/a> on\u00a0Twitter\/X.\u00a0Follow SportsbookWire on Twitter\/X<\/a> and like us on Facebook<\/a>.<\/p>\n Our editors independently choose our recommendations. Some content is produced with paid support from a third party, however our editorial decisions remain independent. If you buy through our links, the USA TODAY Network may earn a commission. Prices and availability may change.<\/p>\n Gambling involves risk. 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