{"id":370121,"date":"2026-06-22T13:02:10","date_gmt":"2026-06-22T13:02:10","guid":{"rendered":"https:\/\/www.newsbeep.com\/us-ca\/370121\/"},"modified":"2026-06-22T13:02:10","modified_gmt":"2026-06-22T13:02:10","slug":"the-u-s-government-secretly-tested-biological-weapons-the-citizens-of-san-francisco-paid-the-price","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us-ca\/370121\/","title":{"rendered":"The U.S. Government Secretly Tested Biological Weapons. The Citizens of San Francisco Paid the Price."},"content":{"rendered":"<p><img src=\"https:\/\/www.popularmechanics.com\/_assets\/design-tokens\/fre\/static\/icons\/clock-regular.4ddebeb.svg\" alt=\"Estimated read time\" width=\"16\" height=\"16\" decoding=\"async\" loading=\"lazy\"\/>3 min read<\/p>\n<p data-journey-content=\"true\" data-node-id=\"0\" class=\"css-1ood0zq emevuu60\">Here\u2019s what you\u2019ll learn when you read this story:<\/p>\n<p>During the early decades of the Cold War, the U.S. government conducted 239 open-air germ warfare tests around the country to assess to dangers of a possible chemical attack on civilian populations.One of the most infamous, known as Operation Sea-Spray, purposefully pumped aerosols of the bacteria Serratia marcescens and Bacillus globigii\u2014both believed to be harmless to humans\u2014over the San Francisco Bay Area.While the operation itself was a success, it\u2019s likely that the test resulted in the death of one man and the sickening of at least 10 others.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"3\" class=\"css-1ood0zq emevuu60\">San Francisco is <a rel=\"noopener nofollow\" href=\"https:\/\/www.lawr.ucdavis.edu\/news\/fog-free-san-francisco-scientists-ponder-californias-climate-future\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.lawr.ucdavis.edu\/news\/fog-free-san-francisco-scientists-ponder-californias-climate-future\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"known for its fog\" data-node-id=\"3.1\" class=\"body-link css-vxmlos emevuu60\">known for its fog<\/a>. Sitting at the intersection of warm air flowing from California\u2019s interior and cool air moving in from the <a href=\"https:\/\/www.popularmechanics.com\/science\/environment\/a19574763\/garbage-patch-fishing\/\" target=\"_self\" data-vars-ga-outbound-link=\"https:\/\/www.popularmechanics.com\/science\/environment\/a19574763\/garbage-patch-fishing\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"Pacific\" data-node-id=\"3.3\" class=\"body-link css-vxmlos emevuu60\" rel=\"nofollow noopener\">Pacific<\/a>, low-lying fog and clouds are a common sight. But in 1950, from September 20 until September 27, a different kind of cloud descended on the city of some 800,000 people\u2014a cloud that had been purposefully released by the U.S. government as a secret bioweapons test.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"4\" class=\"css-1ood0zq emevuu60\">No, this wasn\u2019t some dastardly plan by the government to conduct a macabre experiment on its own citizens. Rather, it was a measure intended to safeguard against other rival nations trying to poison an American city. The government selected San Francisco for its ideal dispersal conditions, tall buildings, and large population, and to pull this off safely, the government relied on the <a href=\"https:\/\/www.popularmechanics.com\/science\/a40459670\/largest-bacteria\/\" target=\"_self\" data-vars-ga-outbound-link=\"https:\/\/www.popularmechanics.com\/science\/a40459670\/largest-bacteria\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"bacteria\" data-node-id=\"4.1\" class=\"body-link css-vxmlos emevuu60\" rel=\"nofollow noopener\">bacteria<\/a> Serratia marcescens and Bacillus globigii\u2014both believed to be harmless to humans.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"7\" class=\"css-1ood0zq emevuu60\">\u201cThey needed something that was, first of all, thought to be harmless,\u201d Matthew Meselson, a molecular biologist from Harvard, <a rel=\"noopener nofollow\" href=\"https:\/\/www.kqed.org\/news\/12062909\/the-true-story-of-the-militarys-secret-1950-san-francisco-biological-weapons-test\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.kqed.org\/news\/12062909\/the-true-story-of-the-militarys-secret-1950-san-francisco-biological-weapons-test\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"told KQED\" data-node-id=\"7.1\" class=\"body-link css-vxmlos emevuu60\">told KQED<\/a> last year, \u201cbecause they certainly didn\u2019t want to kill everybody in <a href=\"https:\/\/www.popularmechanics.com\/culture\/a64730434\/cia-lsd-experiments-operation-midnight-climax\/\" target=\"_self\" data-vars-ga-outbound-link=\"https:\/\/www.popularmechanics.com\/culture\/a64730434\/cia-lsd-experiments-operation-midnight-climax\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"San Francisco\" data-node-id=\"7.3\" class=\"body-link css-vxmlos emevuu60\" rel=\"nofollow noopener\">San Francisco<\/a> or Oakland. And [they also needed something] that could easily be detected by simple methods.\u201d<\/p>\n<p data-journey-content=\"true\" data-node-id=\"8\" class=\"css-1ood0zq emevuu60\">Since the Second Battle of Ypres during World War I, when the German army killed thousands of French Algerian colonial troops by unleashing <a href=\"https:\/\/www.popularmechanics.com\/military\/a23477326\/us-soldier-found-guilty-of-building-exploding-poison-gas-bomb\/\" target=\"_self\" data-vars-ga-outbound-link=\"https:\/\/www.popularmechanics.com\/military\/a23477326\/us-soldier-found-guilty-of-building-exploding-poison-gas-bomb\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"chlorine gas\" data-node-id=\"8.1\" class=\"body-link css-vxmlos emevuu60\" rel=\"nofollow noopener\">chlorine gas<\/a> on April 22, 1915, followed by a second gas attack on Canadian troops two days later, nations had been grappling with the threat of unconventional weapons. With its illusion of geographic imperviousness shattered by the attack on Pearl Harbor on December 7, 1941, the United States moved to address its own vulnerabilities. In 1942, <a rel=\"noopener nofollow\" href=\"https:\/\/www.pbs.org\/wgbh\/americanexperience\/features\/weapon-timeline\/\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.pbs.org\/wgbh\/americanexperience\/features\/weapon-timeline\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"President Franklin Roosevelt\" data-node-id=\"8.3\" class=\"body-link css-vxmlos emevuu60\">President Franklin Roosevelt<\/a> authorized the creation of the first U.S. biological weapons program. Part of the mission of this program was to determine just how vulnerable U.S. cities could be to a biological attack.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"9\" class=\"css-1ood0zq emevuu60\">In 1948, the Committee on Biological Warfare\u2014led by University of Wisconsin bacteriologist Ida Balwin\u2014suggested <a rel=\"noopener nofollow\" href=\"https:\/\/historynet.com\/dr-ira-baldwin-biological-weapons-pioneer\/\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/historynet.com\/dr-ira-baldwin-biological-weapons-pioneer\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"simulating chemical attacks\" data-node-id=\"9.1\" class=\"body-link css-vxmlos emevuu60\">simulating chemical attacks<\/a> through air, water, and infrastructure (such as subway systems) with non-harmful organisms to understand the threat under real environmental conditions. So, two years later, the stage was set for Operation Sea-Spray, and the entire operation almost went without a hitch. Almost.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"11\" class=\"css-1ood0zq emevuu60\">Serratia marcescens is found naturally in water and soils, and it\u2019s known to be harmless to humans. But it isn\u2019t typically sprayed in the air in large quantities, and unfortunately, one of those bacteria-filled <a href=\"https:\/\/www.popularmechanics.com\/science\/environment\/a26553617\/clouds-disappear-study\/\" target=\"_self\" data-vars-ga-outbound-link=\"https:\/\/www.popularmechanics.com\/science\/environment\/a26553617\/clouds-disappear-study\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"clouds\" data-node-id=\"11.2\" class=\"body-link css-vxmlos emevuu60\" rel=\"nofollow noopener\">clouds<\/a> descended on Stanford University Hospital on Clay Street in San Francisco. There, eleven patients developed inexplicable Serratia marcescens infections. In the case of a 75-year-old Irish American named Edward Nevin, who was recovering from prostate surgery, the bacteria found its way to his heart, killing him. Doctors at the hospital were so puzzled that they <a href=\"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/article-abstract\/555999#google_vignette\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/article-abstract\/555999#google_vignette\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"even published a scientific paper\" data-node-id=\"11.6\" class=\"body-link css-vxmlos emevuu60\" rel=\"nofollow noopener\">even published a scientific paper<\/a> regarding the infections in October of the following year.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"12\" class=\"css-1ood0zq emevuu60\">President Richard Nixon <a rel=\"noopener nofollow\" href=\"https:\/\/inss.ndu.edu\/Media\/News\/Article\/693764\/president-nixons-decision-to-renounce-the-us-offensive-biological-weapons-progr\/\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/inss.ndu.edu\/Media\/News\/Article\/693764\/president-nixons-decision-to-renounce-the-us-offensive-biological-weapons-progr\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"ended U.S. research into bioweapons in 1969\" data-node-id=\"12.1\" class=\"body-link css-vxmlos emevuu60\">ended U.S. research into bioweapons in 1969<\/a>, and a treasure trove of information about that research was declassified in the 1970s. It revealed that the U.S. had <a rel=\"noopener nofollow\" href=\"https:\/\/www.washingtonpost.com\/archive\/politics\/1980\/04\/22\/army-report-details-germ-war-exercise-in-ny-subway-in-66\/70772a8b-8223-47de-99b4-876d5e57dd9c\/\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.washingtonpost.com\/archive\/politics\/1980\/04\/22\/army-report-details-germ-war-exercise-in-ny-subway-in-66\/70772a8b-8223-47de-99b4-876d5e57dd9c\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"performed 239 open-air germ warfare tests\" data-node-id=\"12.3\" class=\"body-link css-vxmlos emevuu60\">performed 239 open-air germ warfare tests<\/a> around the country, including in the subway in <a href=\"https:\/\/www.popularmechanics.com\/science\/a71242455\/giant-hot-blob-heading-toward-new-york-city\/\" target=\"_self\" data-vars-ga-outbound-link=\"https:\/\/www.popularmechanics.com\/science\/a71242455\/giant-hot-blob-heading-toward-new-york-city\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"New York City\" data-node-id=\"12.5\" class=\"body-link css-vxmlos emevuu60\" rel=\"nofollow noopener\">New York City<\/a>, on the Pennsylvania turnpike, and in the national airport in Washington D.C. According to KQED, Edward Nevin III\u2014the grandson of the man who died during the faux attack\u2014read these reports and decided to sue the U.S. government, even though he accurately foresaw that <a rel=\"nofollow noopener\" href=\"https:\/\/www.nytimes.com\/1983\/01\/18\/us\/suits-barred-in-germ-test-death.html#:~:text=In%20May%201981%2C%20Federal%20District,Gate%20Bridge%20in%20September%201950.\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.nytimes.com\/1983\/01\/18\/us\/suits-barred-in-germ-test-death.html#:~:text=In%20May%201981%2C%20Federal%20District,Gate%20Bridge%20in%20September%201950.\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"he\u2019d eventually lose\" data-vars-ga-product-id=\"d578083b-bbac-4bc2-89ac-93abf65abc82\" data-node-id=\"12.7\" data-href=\"https:\/\/www.nytimes.com\/1983\/01\/18\/us\/suits-barred-in-germ-test-death.html#:~:text=In%20May%201981%2C%20Federal%20District,Gate%20Bridge%20in%20September%201950.\" data-product-url=\"https:\/\/www.nytimes.com\/1983\/01\/18\/us\/suits-barred-in-germ-test-death.html#:~:text=In%20May%201981%2C%20Federal%20District,Gate%20Bridge%20in%20September%201950.\" data-affiliate=\"false\" data-affiliate-network=\"\" data-fp-affiliate-inline-link=\"false\" data-fp-affiliate-button-link=\"false\" data-vars-ga-product-price=\"$0.00\" data-vars-ga-product-retailer-id=\"a79190f9-4bed-4550-b0a8-793d6144a06b\" data-vars-ga-link-treatment=\"(not set) | (not set)\" class=\"body-link product-links css-vxmlos e1aq0z090\" data->he\u2019d eventually lose<\/a>.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"13\" class=\"css-1ood0zq emevuu60\">\u201cBut we still had to tell the story,\u201d he told KQED. \u201cTo have a citizen submitted to that kind of risk is awful.\u201d<\/p>\n<p><img src=\"https:\/\/www.newsbeep.com\/us-ca\/wp-content\/uploads\/2026\/06\/e9b7a87b-359a-4fff-859b-ab9cf5e31c5b_1565789938.file.png\" alt=\"Headshot of Darren Orf\" title=\"Headshot of Darren Orf\" width=\"100%\" height=\"100%\" decoding=\"async\" loading=\"lazy\" class=\"css-o0wq4v ev8dhu53\"\/><\/p>\n<p>Darren lives in Portland, has a cat, and writes\/edits about sci-fi and how our world works. You can find his previous stuff at Gizmodo and Paste if you look hard enough.\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"3 min read Here\u2019s what you\u2019ll learn when you read this story: During the early decades of the&hellip;\n","protected":false},"author":2,"featured_media":370122,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[47544,150061,9569,124165,150062,9568,87063,101,103,102,104,106,105,150060,126789],"class_list":["post-370121","post","type-post","status-publish","format-standard","has-post-thumbnail","category-san-francisco","tag-content-type-news","tag-contentid-c7d8e6ab-0e5f-4c0f-b350-c7929a0d4cb7","tag-displaytype-standard-article","tag-issyndicated-false","tag-listen_time-285","tag-locale-us","tag-read_time-4","tag-san-francisco","tag-san-francisco-headlines","tag-san-francisco-news","tag-sf","tag-sf-headlines","tag-sf-news","tag-shorttitle-inside-the-secret-bioweapons-test-on-san-francisco","tag-subsection-weapons"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts\/370121","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/comments?post=370121"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts\/370121\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/media\/370122"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/media?parent=370121"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/categories?post=370121"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/tags?post=370121"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}