Tarailo and her husband, Jeff, breathed a sigh of relief. To further improve the chances of it not returning, Tarailo chose to have a radical mastectomy, then reconstruction surgery.<\/p>\n
Cancer-free years fly by
\n![\"Woman](\"https:\/\/www.newsbeep.com\/us-ca\/wp-content\/uploads\/2026\/06\/family-holds-hands-with-girl-scout-in-front-of-tree-body1.jpg\")
\nBreast cancer clinical trial patient Jamie Lynne Tarailo and her husband, Jeff Tarailo, with their daughter Zoey.<\/p>\n
Before long, the Placerville family continued with their busy lives. Tarailo became a Girl Scout leader. Her daughter, Zoey, and her friends in the troop earned pink breast cancer awareness patches to show their support and raise awareness of breast cancer.<\/p>\n
Tarailo even enrolled in nursing school in hopes of advancing her career from licensed vocational nurse to registered nurse.<\/p>\n
Fast forward to September 2025. The couple, who were high school sweethearts at Union Mine High School in El Dorado, were preparing for their 20th\u00a0year high school reunion.<\/p>\n
\u201cI went to help my daughter with a puzzle on the floor and felt as if I had pulled a muscle,\u201d Tarailo said.<\/p>\n
Burning pain followed and she called her doctor. This time the biopsy results were very worrisome. The cancer was back and it had invaded the lymph nodes. A\u00a0PET scan<\/a>\u00a0also showed the cancer had metastasized, or spread, to her bones.<\/p>\n Devastated, Tarailo was told in February that her breast cancer was at stage four, the most advanced form of the disease.<\/p>\n Cancer care in Cameron Park + UC Davis medical campus Tarailo was a patient at\u00a0Marshall<\/a>\u00a0where she was also a nurse. She believed in the power of medicine. So, when her Marshall oncologist suggested she also see an oncologist at\u00a0UC Davis Comprehensive Cancer Center<\/a>, she was open to learning more. As a\u00a0UC Davis Cancer Care Network<\/a>\u00a0affiliate,\u00a0Marshall Cancer Center<\/a>\u00a0enrolls patients in the latest clinical trials that typically are only available at academic medical centers.<\/p>\n At\u00a0UC Davis Comprehensive Cancer Center,<\/a>\u00a0Tarailo met with\u00a0Mili Arora<\/a>, an oncologist based at the\u00a0UC Davis Health<\/a>\u00a0campus in Sacramento. Arora is leading an important clinical trial that she thought would be the best option for Tarailo.<\/p>\n \u201cDr. Arora was so personable and answered all my questions,\u201d Tarailo said. \u201cI really liked and trusted her.\u201d<\/p>\n FourLight-3 clinical trial becomes first industry-sponsored clinical trial at a CCN<\/p>\n Tarailo agreed to enroll in the first industry-sponsored clinical trial to be available at a CCN.<\/p>\n Sponsored by\u00a0Pfizer<\/a>, the\u00a0FourLight\u20113 trial<\/a>\u00a0compares a next-generation\u00a0CDK4 inhibitor<\/a>\u00a0called\u00a0atirmociclib<\/a>\u00a0plus\u00a0letrozole<\/a>\u00a0against standard of care CDK4\/6 inhibitors combined with letrozole.<\/p>\n Tarailo enrolled in the FourLight-3 trial because she was hopeful for a better treatment option than the standard of care and she knew it would help other women in the future.<\/p>\n \u201cJamie Lynne is committed to making a difference,\u201d Arora said. \u201cWe can\u2019t move the needle in the cancer fight without the bravery of our trial participants and we do think the FourLight-3 clinical trial could transform care for the type of breast cancer that Jamie Lynne’s has been diagnosed with.\u201d<\/p>\n HR\u2011positive, HER2\u2011negative disease represents the most common subtype of breast cancer. Over the past decade, the introduction of CDK4\/6 inhibitors combined with hormone therapy has significantly improved progression\u2011free survival and quality of life. However, these agents are associated with severe side effects \u2014 such as low white blood cell count, diarrhea and fatigue \u2014 that can limit long\u2011term use. The FourLight\u20113 study will help determine whether a more selective CDK4 inhibitor could be more efficient and easier to tolerate.<\/p>\n \u201cThe oncology community is closely watching FourLight\u20113 as a potential step forward in the evolution of endocrine\u2011based combination therapy,\u201d Arora said. \u201cIf successful, FourLight\u20113 could give us a first\u2011line option that allows greater flexibility in tailoring therapy and better quality of life.\u201d<\/p>\n In other words, the clinical trial could mark a shift toward precision within targeted cancer treatments \u2014 seeking not just stronger drugs, but smarter ones.<\/p>\n \u201cFourLight\u20113 could offer a new standard of care for upfront metastatic HR+\/HER2- breast cancer. This paradigm shift will have implications for thousands of women worldwide,\u201d Arora said. \u201cWe appreciate brave women like Jamie Lynne who are participating in this important clinical trial.\u201d<\/p>\n Best of both worlds<\/p>\n Tarailo is thrilled about receiving care in two places.<\/p>\n \u201cI am so grateful to keep my Marshall oncologist and primary care doctor and still be able to get access to the most advanced treatments at UC Davis,\u201d Tarailo said. \u201cIt feels like I\u2019m \u2018two-timing\u2019 by getting cancer care at both Marshall and UC Davis, but I feel fortunate.\u201d<\/p>\n While continuing to see Arora in Sacramento, Tarailo still visits her oncologist at Marshall in Cameron Park where she also gets her lab tests and picks up the clinical trial oral drug combination.<\/p>\n It\u2019s the best of both worlds, Tarailo said, because she avoids the hour-long drive from Placerville to Sacramento for most of her cancer care.<\/p>\n \u201cAnd I get to maintain relationships with Marshall staff who have become an important support system,\u201d she added.<\/p>\n Because Tarailo is young, she may be on the targeted therapy for a long time and is encouraged by the possibility of fewer side effects.<\/p>\n \u201cWhen it comes to attitude, Jamie Lynne\u2019s perspective is what we like to see,\u201d said Arora. \u201cShe\u2019s a fighter and remains upbeat, which will help her navigate her treatment in the best possible way. It is patients like her, willing to participates in clinical trials, who give us the edge in conquering cancer.\u201d<\/p>\n UC Davis Comprehensive Cancer Center<\/p>\n UC Davis Comprehensive Cancer Center is the only National Cancer Institute-designated center serving the Central Valley and inland Northern California, a region of more than 6 million people. Its specialists provide compassionate, comprehensive care for more than 100,000 adults and children every year and access to more than 200 active clinical trials at any given time. Its innovative research program engages more than 240 scientists at UC Davis who work collaboratively to advance discovery of new tools to diagnose and treat cancer. Patients have access to leading-edge care, including immunotherapy and other targeted treatments. Its Office of Community Outreach and Engagement addresses disparities in cancer outcomes across diverse populations, and the cancer center provides comprehensive education and workforce development programs for the next generation of clinicians and scientists. For more information, visit cancer.ucdavis.edu<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"(SACRAMENTO) New mom Jamie Lynne Tarailo was only 34, busy with a 2-year-old toddler and a career, when…\n","protected":false},"author":2,"featured_media":376393,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32],"tags":[121,123,122],"class_list":["post-377206","post","type-post","status-publish","format-standard","has-post-thumbnail","category-sacramento","tag-sacramento","tag-sacramento-headlines","tag-sacramento-news"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts\/377206","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/comments?post=377206"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/posts\/377206\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/media\/376393"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/media?parent=377206"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/categories?post=377206"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ca\/wp-json\/wp\/v2\/tags?post=377206"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\n![\"Exterior](\"https:\/\/www.newsbeep.com\/us-ca\/wp-content\/uploads\/2026\/06\/marshall-cancer-center-sign-and-entrance-body3.jpg\")
\nMarshall Cancer Center is a UC Davis Cancer Care Network affiliate in Cameron Park.<\/p>\n![\"Headshot](\"https:\/\/www.newsbeep.com\/us-ca\/wp-content\/uploads\/2026\/06\/jamie-lynne-pullq.jpg\")
It feels like I\u2019m \u2018two-timing\u2019 by getting cancer care at both Marshall and UC Davis, but I feel fortunate.\u201d\u2014Jamie Lynne Tarailo breast cancer clinical trial patientHR-positive, HER2-negative breast cancer<\/p>\n![\"Blonde](\"https:\/\/www.newsbeep.com\/us-ca\/wp-content\/uploads\/2026\/06\/provider-talks-with-patient-in-exam-room-body2.jpg\")
\nJamie Lynne Tarailo talks to UC Davis Health oncologist Deepthi Busayavalasa who is based at Marshall Cancer Center.<\/p>\n