Spread<\/p>\n
Broncos +3 (-120)\u00a049ers -3 (+100)<\/p>\n
Moneyline<\/p>\n
Total<\/p>\n
47.5 (Over -110\/Under -110)<\/p>\n
There has been a little line movement in this game since it opened with the 49ers as 3-point favorites<\/a>. San Francisco remains in that spot, but the odds (-120 on Denver +3) have shifted slightly towards the Broncos after their win against the Los Angeles Rams in Week 3. Plus, the total has jumped from 45.5 to 47.5 \u2013 a notable swing \u2013 since Sunday night.\u00a0<\/p>\n Broncos vs. 49ers Score Prediction\u00a0<\/p>\n SI Betting\u2019s Iain MacMillan shares his favorite bet for every game, every week in his Road to 272 column<\/a>, and he\u2019s taking the 49ers to cover:\u00a0<\/p>\n By a lot of metrics, the San Francisco 49ers are the best team in the NFL through the first three weeks. They are first in Net Yards per Play (+2.5), first in EPA per play, and first in success rate. To be fair, two of their first three games came against the Dolphins and Cardinals, but I’m extremely high on this team.<\/p>\n Now they get to face a Broncos team that I’m still not sold on. They managed to win two games at home, a historically tough place for opponents to play in September, and the game against the Rams finished with a handful of questionable calls that went Denver’s way. Overall, the Broncos are 25th in Net Yards per Play (-0.6), and Bo Nix is just 26th in adjusted EPA per play and 27th in completion percentage over expected.<\/p>\n With the spread below a field goal, I think the 49ers are a great bet on their home field.<\/p>\n MacMillan and I actually happen to be on opposite sides in this game<\/a>, but I do think the 49ers will win \u2013 even if they don\u2019t cover.\u00a0<\/p>\n I\u2019m worried about this San Francisco defense without Bosa (and potentially Dre Greenlaw) against a Denver team that is a lot better than Miami and Arizona. The 49ers are just 19th in success rate and 15th in EPA\/Play this season, a shaky ranking since they\u2019ve faced two of the worst teams in the NFL.<\/p>\n Meanwhile, Denver is 10th in EPA\/Pass despite facing three quarterbacks in the MVP conversation. The Bronco offense hasn\u2019t been anywhere near as good as the 49ers, but is San Francisco\u2019s offense being propped up by favorable matchups?<\/p>\n The Broncos have shown they aren\u2019t going to roll over even if they fall behind, and Arizona was able to orchestrate a backdoor cover against the 49ers in Week 3. If San Francisco struggles to get stops, I could see this game coming down to the final possession.\u00a0<\/p>\n Final Score Prediction: 49ers 27, Broncos 26<\/p>\n Odds refresh periodically and are subject to change.<\/p>\n If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.<\/p>\n Claim the latest\u00a0DraftKings promo code<\/a>\u00a0offer today. Sign up and get\u00a0$150 in bonus bets instantly when you make your first $5 bet.<\/a><\/p>\n
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