More than 15,000 runners are expected to hit the road through downtown Jacksonville, San Marco and St. Nicholas for the 49th annual Gate River Run on Saturday morning, March 7.

And where runners are running, cars won’t.

The Jacksonville Sheriff’s Office will be closing numerous roads near the heart of the city, including two of the five major downtown bridges across the St. Johns River, for the 15-kilometer race.

Some of the closures last for only a short time, such as the Main Street Bridge, but others will remain out of service to vehicular traffic throughout the morning.

In addition to runners, the road closures could complicate travel for drivers heading to other events like the Jacksonville Home & Patio Show at the Prime Osborn Convention Center or the ASUN women’s basketball tournament semifinals at VyStar Veterans Memorial Arena. The latter tips off at 11 a.m. March 7, only a couple of blocks from the finish line, and during a time when thousands of runners will still remain on or near the course.

Which Jacksonville roads are closed for the 2026 Gate River Run?

Bay Street, from Liberty Street to Jacksonville Shipyards, 10 a.m. March 6 to 2 p.m. March 7

Gator Bowl Boulevard, Hart Bridge ramp to A. Philip Randolph Boulevard, 10 a.m. March 6 to 2 p.m. March 7

Hart Bridge, southeast-bound, from Duval Street to Atlantic Boulevard, 7:45 a.m. to 11:30 a.m.

Duval Street, from Jacksonville Fairgrounds to Main Street Bridge), 7:15 a.m. to 8:45 a.m.

A. Philip Randolph Boulevard, from Adams Street to Bay Street, 7:15 a.m. to 9 a.m.

Main Street Bridge, full length, 7:45 a.m. to 9 a.m.

Riverplace Boulevard and Prudential Drive, 8 a.m. to 9:15 a.m.

San Marco Boulevard, from Prudential Drive to Laverne Street, 8 a.m. to 9:30 a.m.

River Road and River Oaks Road, 8:15 a.m. to 9:45 a.m.

Hendricks Avenue, from River Oaks Road to Alexandria Place, 8:20 a.m. to 10 a.m.

Alexandria Place and Belote Place, 8:20 a.m. to 10:15 a.m.

Atlantic Boulevard westbound, from Belote Place to Holmesdale Street, 8:20 a.m. to 10:30 a.m.

Holmesdale Road, Nicholson Road, Olive Street and Gay Avenue, 8:20 a.m. to 10:45 a.m.

Altantic Boulevard westbound, from Gay Avenue to Hart Bridge, 8:20 a.m. to 11:00 a.m.

This article originally appeared on Florida Times-Union: Gate River Run road closures in Jacksonville