Attendance is expected to top 100,000 over the two-day event, which consistently ranks among the largest outdoor festivals in St. Pete.
In 2025, Sunshine Artist Magazine included Mainsail among the top fine art shows in the country.
Beyond the artist booths, the festival features a full lineup of live music, a food court and beer garden, and a range of family-friendly programming.
The Junior League of St. Petersburg will host its Kids Create craft tent, offering five free make and take crafts.
Additionally, the Young at Art Student Exhibition will highlight work from Pinellas County students.
Artists will compete for $60,000 in total prize money, including a $10,000 Best of Show award.