STUART, Fla. (CBS12) — A wrong-way pursuit on U.S. 1 ended in a serious crash early Tuesday morning after a driver accused of fleeing Stuart police drove into oncoming traffic, authorities said.

The driver, a 15-year-old juvenile, and the other motorist were both seriously injured in the crash, which happened around 3:45 a.m. Tuesday, according to the Stuart Police Department.

Officers say they were conducting traffic enforcement near Southwest Federal Highway and Southwest St. Lucie Crescent when they spotted a vehicle traveling north at an extremely high rate of speed, police said.

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An officer attempted to stop the vehicle, but the driver refused to pull over and sped away, prompting a pursuit.

The chase eventually continued onto U.S. 1, where the driver began traveling north in the southbound lanes from Wright Boulevard, according to police.

Officers continued trying to stop the vehicle and attempted to alert other motorists to the danger. The driver continued traveling the wrong way before crashing into a vehicle heading south on Northwest Federal Highway near the Mall South Entrance intersection, police said.

Both drivers were taken to Lawnwood Medical Center in Fort Pierce with serious injuries.

The Stuart Police Department is investigating the pursuit, while the Florida Highway Patrol is conducting a separate investigation into the crash.

Police said no additional information would be released while the investigations remain ongoing.