Two of the better teams in Conference USA clash when the Delaware Blue Hens battle the Jacksonville State Gamecocks on Wednesday night. Delaware is coming off a 27-24 loss to Western Kentucky on Oct. 3, while Jacksonville State held off Sam Houston State 29-27 on Thursday. The Blue Hens (3-2, 1-1 C-USA), who are in their first year in the conference, are 1-1 on the road this season. The Gamecocks (3-3, 2-0 C-USA), who have a plus-16 point differential, are 2-0 on their home field in 2025.

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Kickoff from AmFirst Stadium in Jacksonville, Ala., is at 7 p.m. ET. Delaware leads the all-time series 2-0. The Blue Hens are 3-point favorites in the latest Delaware vs. Jacksonville State odds, while the over/under for total points scored is 57.5 via SportsLine consensus.

Before making any Delaware vs. Jacksonville State picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and is a profitable 39-27 combined on money-line and over/under picks since the beginning of 2024. Anyone following at sportsbooks and on betting apps could have seen STRONG returns!

The model has simulated Delaware vs. Jacksonville State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits in well over 70% of simulations.

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