The LA Rams (4-2) and Jacksonville Jaguars (4-2) meet Sunday for a Week 7 game at Wembley Stadium in London, United Kingdom. Kickoff is scheduled for 9:30 a.m. ET (NFL Network / NFL+). Let’s analyze BetMGM Sportsbook’s NFL odds around the Rams vs. Jaguars odds and make our expert NFL picks and predictions for the best bets.

The Rams have won the past 3 meetings between these organizations, including a 37-7 win in Los Angeles Dec. 5, 2021, as a 13-point favorite as the Under (48) cashed.

L.A. went to Baltimore last Sunday, winning 17-3 in a misty, cloudy and cool day, covering as a 7.5-point favorite as the Under (45) cashed. QB Matthew Stafford threw for 181 yards and a TD, while RB Kyren Williams rushed for 50 yards and a TD. TE Tyler Higbee had 4 receptions for a team-high 40 yards with a score. WR Puka Nacua (foot) left with a foot injury, ending up with 2 grabs and 28 yards on 3 targets. He has already been ruled OUT for Sunday’s game.

The Rams stayed in Baltimore to practice, before traveling to London to battle the Jaguars. As a favorite this season, L.A. is 4-1 against the spread (ATS) in 5 games this season. The Rams are 4-0 SU/ATS in 4 games against AFC opponents this season, while going 0-2 SU/ATS in 2 games vs. NFC. The Under is 3-1 vs. AFC, while the Over is 2-0 vs. NFC.

The Jaguars suffered a 20-12 loss as 1-point underdogs last Sunday at home as the Under (47.5) cashed. QB Trevor Lawrence threw for 258 yards and 2 TDs, including 8 receptions for 90 yards and a TD for WR Brian Thomas Jr. Still, Jacksonville is 2-1 SU/ATS in 3 games vs. NFC teams, while the Under is 2-1 in those outings.

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This is the fifth international game of the season, and the fourth in either Ireland or the United Kingdom. Underdogs are 3-1 ATS in the previous 4 international games, while the Over is 3-1.

Watch the NFL on Fubo!Rams vs. Jaguars odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 12:25 p.m. ET.

Moneyline (ML): Rams -160 (bet $160 to win $100) | Jaguars +135 (bet $100 to win $135)Against the spread: Rams -3 (-110) | Jaguars +3 (-110)Over/Under (O/U): 44.5 (O: -110 | U: -110)Rams vs. Jaguars injuries

Rams

OL Rob Havenstein (ankle) outWR Puka Nacua (foot) out

Jaguars

LB Devin Lloyd (calf) outTE Quintin Morris (groin) outRams vs. Jaguars picks and predictionsPrediction

Jaguars 23, Rams 20

The JAGUARS (+135) are moderate underdogs in this battle in London, and they catch a major break with Nacua being sidelined.

Nacua had 8 or more receptions in each of his first 5 full games, with 10 or more receptions in 4 of those outings. He had been one of the best, if not the best, receivers in the game. With Nacua sidelined, veteran WR Davante Adams must step up and try to fill his shoes, with WR Tutu Atwell perhaps becoming more of a downfield threat.

The JAGUARS +3 (-110) are worth a look, if you want a little bit of wiggle room, and you foresee a close game with a margin of victory of 1 or 2 points. It’s certainly possible.

If Nacua was playing, I’d like the Rams an awful lot, but expect the Jaguars to key in on Williams quite a bit. Jacksonville is pretty strong against the run, allowing just 91.5 rushing yards per game, 8th in the NFL. It’s the one thing the Jacksonville defense actually does well.

UNDER 44.5 (-110) is the lean, but go with a half-unit play at most.

Last week, the Rams handed the first Under result of the season to the Ravens. It was the first Under result away from home in 3 tries for L.A. The Over-Under has split 2-2 vs. AFC for the Rams, too. The Over-Under has split 3-3 for the Jaguars, while the Under is 2-1 vs. NFC.

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