Jaguars at Cardinals odds, picks and predictions

The Jacksonville Jaguars (6-4) visit the Arizona Cardinals (3-7) Sunday in Week 12 NFL action. Kickoff from State Farm Stadium in Glendale, Arizona, is at 4:05 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Jaguars vs. Cardinals odds and make our expert NFL picks and predictions for the best bets.

The Jags have won 2 of their last 3 games and have scored at least 29 points in 3 straight. They are coming off a 35-6 blowout home win over the LA Chargers last Sunday as 3-point underdogs with the Under (43.5) cashing. They held the Chargers to only 135 yards of total offense and rushed for 192 yards as a team.

The Cardinals have lost 2 straight games and are 1-7 in their last 8 games. They lost 41-22 at home last week to the San Francisco 49ers as 3.5-point underdogs with the Over (48.5) cashing. QB Jacoby Brissett set an NFL record with 47 pass completions for 452 passing yards, and he had 2 TD passes for the fifth consecutive game, but he had 2 turnovers for the second straight game and the Cardinals fell behind 35-10 after falling behind 35-0 to the Seattle Seahawks in Week 10.

The Cardinals are 4-2 all-time against Jacksonville, and they beat the Jags 31-19 as 7.5-point road favorites with the Under (52) cashing in their last meeting in 2021.

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Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 10:44 p.m. ET.

Moneyline (ML): Jaguars -135 (bet $135 to win $100) | Cardinals +115 (bet $100 to win $115)Against the spread (ATS): Jaguars -2.5 (-105) | Cardinals +2.5 (-115)Over/Under (O/U): 47.5 (O: -110 | U: -110)Jaguars at Cardinals key injuries

Jaguars

OL Anton Harrison (knee, ankle) outCB Jourdan Lewis (neck) questionableTE Hunter Long (hip, knee) outT Benton Strange (hip) questionableWR Brian Thomas Jr. (ankle) outDE Travon Walker (knee) out

Cardinals

OL Kelvin Beachum (groin) questionableRB Trey Benson (knee) questionableOLB Baron Browning (concussion) outRB Emari Demercado (ankle) outWR Marvin Harrison Jr. (illness) outOL Will Hernandez (knee) questionableCB Will Johnson (back, hip) questionableDL Darius Robinson (groin) questionableCB Garrett Williams (ankle) questionableJaguars at Cardinals picks and predictionsPrediction

Jaguars 31, Cardinals 24

The Cardinals are only 1-4 at home and haven’t won there since Week 2. They have allowed 27 or more points in 4 of their last 5 games, but have not scored more than 27.

The Cardinals have allowed over 120 rushing yards in 3 of their last 5 games, while the Jaguars have more than 150 in 2 of their last 3 games. They don’t run the ball well and have 4 turnovers in their last 2 games.

The Jags will win, but you will get better value from the spread, as it is only 2.5 points.

PASS.

All 4 of the Cardinals’ losses since Brissett took over the starting job have been by at least 4 points and their last 2 games have been losses by 19 and 22 points.

The Jags are 5-0-1 ATS in their 6 wins.

BET JAGUARS -2.5 (-105).

The Cardinals have not scored fewer than 22 points in Brissett’s 5 starts. The Jaguars have scored 29 or more in 3 straight. The Cardinals have allowed over 40 in 2 straight games.

BET OVER 47.5 (-110).

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Jaguars at Cardinals odds, picks and predictions

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