James Cook is really good. So is the Jaguars’ defense.<\/p>\n
Those elements are the core perhaps the No. 1 matchup in Jaguars-Bills Sunday, with the Bills and running back James Cook entering as the NFL’s No. 1 running offense and the Jaguars entering as the NFL’s No. 1 rushing defense.<\/p>\n
It’s strength versus strength \u2013 and Cook, the NFL’s leading rusher in 2025, is really strong.<\/p>\n
“He’s an elite back,” Campanile said.<\/p>\n
Cook, a fourth-year veteran, rushed for 1,621 yards and 12 touchdowns this season for a Bills offense that rushed for 159.6 yards per game. The Jaguars allowed 85.6 yards per game and did not allow a runner to rush for more than 75 yards in a game.<\/p>\n
“They challenge you in so many ways with their run game,” Campanile said. “They make everybody tackle. They do a really good job in their combinations. They do a good job playing with their hands as an offensive line. Their perimeter does a really good job blocking. That’s generated a lot of their runs downfield.<\/p>\n
“It’s a challenge at every level of the defense.”<\/p>\n","protected":false},"excerpt":{"rendered":"James Cook is really good. So is the Jaguars’ defense. Those elements are the core perhaps the No.…\n","protected":false},"author":2,"featured_media":111512,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[20267,54888,881,20266,116,118,117,885,5323,880,883],"class_list":["post-111511","post","type-post","status-publish","format-standard","has-post-thumbnail","category-jacksonville","tag-anthony-campanile","tag-buffalo-bills-at-jacksonville-jaguars-2025-post-1","tag-front-page-headline","tag-grant-udinski","tag-jacksonville","tag-jacksonville-headlines","tag-jacksonville-news","tag-john-oehser","tag-liam-coen","tag-news-front-page-headline","tag-news-jaguars-news"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/posts\/111511","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/comments?post=111511"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/posts\/111511\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/media\/111512"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/media?parent=111511"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/categories?post=111511"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/tags?post=111511"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}