March 21, 2026Updated March 22, 2026, 3:44 a.m. ET<\/p>\n
The Miami Hurricanes (26-8) meet the Purdue Boilermakers<\/a> (28-8) Sunday in a second-round NCAA Tournament West Region game. Tip from Enterprise Center in St. Louis, Missouri, is scheduled for 12:10 p.m. ET (CBS). Let’s analyze NCAA basketball odds around the Miami vs. Purdue and make our expert college basketball picks and predictions<\/a> for the best bets.<\/p>\n The 7-seed Canes quieted the home-crowd-fueled Missouri Tigers 80-66 Friday, covering as 1.5-point favorites with the Over (145.5) going to the bank. F Malik Reneau led the way with 24 points and 6 boards. They outrebounded Mizzou 46-30, which spawned 19 second-chance points.<\/p>\n Second-seeded Purdue dethroned the Queens Royals Friday 104-71, covering as 25.5-point favorites as the Over (159.5) cashed. G Braden Smith led the way with 26 points and 8 assists and F Trey Kaufman-Renn added 25 points and 9 boards. Smith’s 8 dimes broke the Division I record for career assists, formerly held by Duke’s Bobby Hurley. Smith now has 1,083 assists in 146 games (7.41 per game average)<\/p>\n These teams last met up Dec. 8, 2020, when Miami covered as 2.5-point dogs in a 58-54 home win. Purdue beat them in 2011 in a 76-65 final.<\/p>\n \u2013\u00a0Rankings:\u00a0USA TODAY Sports Coaches Poll<\/a><\/p>\n Watch NCAA basketball on Fubo!<\/a>Miami vs. Purdue odds<\/p>\n Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub<\/a> for a full list. Lines last updated at Saturday at 10:25 p.m. ET.<\/p>\n Moneyline (ML): Miami +280 (bet $100 to win $280) | Purdue -350 (bet $350 to win $100)Against the spread (ATS): Miami +7.5 (-105) | Purdue -7.5 (-115)Over\/Under (O\/U): 148.5 (O: -105 | U: -115)Miami vs. Purdue picks and predictionsPrediction<\/p>\n Purdue 81, Miami 78<\/p>\n There’s no play here with Purdue such heavy favorites — and rightfully so. There is a prop bet that sticks out, though. Take Miami F MALIK RENEAU UNDER 6.5 REBOUNDS (-118). He hasn’t recorded 7 boards in 4 straight games and has only done so twice in his last 10.<\/p>\n Purdue is just 4-6 ATS in its last 10 despite covering in 3 of 4. Meanwhile, Miami is 7-3 ATS in its last 10. The Canes are a well-rounded team, 53rd in the country with 81.9 points per game (PPG) and tied for 62nd in defensive rating. They’ll hang around before the supremely talented Boilers eventually clinch it.<\/p>\n Go with MIAMI +7.5 (-105).<\/p>\n Both of these teams score in bunches. Purdue is 7-3 O\/U in its last 10, and Miami has gone north of the total in 3 of 4. This is a fair number.<\/p>\n Go OVER 148.5 (-105).<\/p>\n For more sports betting picks and tips, check out SportsbookWire.com<\/a> and BetFTW<\/a>.<\/p>\n Follow @rdodsonsports on\u00a0Twitter\/X<\/a>. 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