{"id":86859,"date":"2025-12-17T16:56:09","date_gmt":"2025-12-17T16:56:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/us-fl\/86859\/"},"modified":"2025-12-17T16:56:09","modified_gmt":"2025-12-17T16:56:09","slug":"usf-vs-old-dominion-prediction-odds-spread-line-2025-cure-bowl-picks-from-proven-model","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us-fl\/86859\/","title":{"rendered":"USF vs. Old Dominion prediction, odds, spread, line: 2025 Cure Bowl picks from proven model"},"content":{"rendered":"

The Old Dominion Monarchs<\/a> face the South Florida Bulls<\/a> in the 2025 Cure Bowl on Wednesday. Old Dominion closed the regular season with five consecutive wins, while USF won its last two games and three of four. The Monarchs (9-3), who finished second in the Sun Belt East Division at 6-2, outscored their opponents by 161 points this season. The Bulls (9-3), who finished tied for fourth in the American Conference, outscored their foes by 236 points in 2025. South Florida quarterback Byrum Brown and Old Dominion quarterback Colton Joseph have both opted out and will not take part in the game. South Florida coach Alex Golesh and most of the offensive staff will also not coach since Golesh took the Auburn job.<\/p>\n

Kickoff from Camping World Stadium in Orlando, Fla., is at 5 p.m. ET. This will be the first-ever meeting. The Bulls are 3-point favorites in the latest Old Dominion vs. South Florida odds, while the over\/under for total points scored is 52.5 via SportsLine consensus. Before making any Old Dominion vs. South Florida picks,\u00a0check out the college football predictions from the SportsLine Projection Model<\/a>.\u00a0<\/p>\n

New users can target the\u00a0DraftKings promo code<\/a>, which offers\u00a0$200 in bonus bets if your $5+ bet wins<\/a>:<\/p>\n

The model simulates every FBS game 10,000 times, and it is profitable on its top-rated money-line picks since the beginning of the 2024 season. Anybody following those\u00a0college football betting<\/a>\u00a0picks at\u00a0sportsbooks<\/a>\u00a0and on\u00a0betting sites<\/a>\u00a0could have seen strong returns.<\/p>\n

Now, the model has set its sights on Old Dominion vs. South Florida<\/a>. You can visit SportsLine now to see the picks<\/a>. Here are the FBS college football odds<\/a> and trends for USF vs. Old Dominion:<\/p>\n

Old Dominion vs. South Florida spread<\/p>\n

USF -3 at DraftKings Sportsbook<\/p>\n

Old Dominion vs. South Florida over\/under<\/p>\n

52.5 points<\/p>\n

Old Dominion vs. South Florida money line\u00a0<\/p>\n

USF -151, Old Dominion +127<\/p>\n

Old Dominion vs. South Florida picks<\/p>\n

See picks at SportsLine<\/a><\/p>\n

Old Dominion vs. South Florida streaming\u00a0<\/p>\n

Fubo<\/a>\u00a0(Try for free) \u00a0<\/p>\n

New users can also check out the latest\u00a0FanDuel promo code<\/a>\u00a0and\u00a0get $250 in bonus bets at FanDuel if your $5 bet wins<\/a>.\u00a0<\/p>\n

How to make Old Dominion vs. South Florida picks<\/p>\n

After 10,000 simulations of this matchup SportsLine’s model is going Over (52.5) on the total. The Bulls have gone over the total in three of their last five games and in seven of 10.\u00a0<\/p>\n

The model has Old Dominion running back Trequan Jones<\/a> rushing for more than 80 yards and a score, while South Florida running backs Nykahi Davenport<\/a>, Sam Franklin<\/a> and Alvon Isaac<\/a> combined to rush for more than 100 yards. The teams combine for 56 points as the Over clears in well over 50% of simulations.<\/p>\n

The model also says one side of the spread hits well over 50% of the time.\u00a0You can see the model’s pick at SportsLine<\/a>. \u00a0<\/p>\n

So who wins Old Dominion vs. South Florida, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the Old Dominion vs. South Florida spread to jump on, all from the advanced model that’s up on its top-ranked money-line picks<\/a>, and find out.<\/p>\n","protected":false},"excerpt":{"rendered":"The Old Dominion Monarchs face the South Florida Bulls in the 2025 Cure Bowl on Wednesday. Old Dominion…\n","protected":false},"author":2,"featured_media":86860,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[4640,143,47316,47318,47317,28,30,29,22109,47314,47313,47315,6782],"class_list":["post-86859","post","type-post","status-publish","format-standard","has-post-thumbnail","category-florida","tag-betting","tag-college-football","tag-cure-bowl-game-odds","tag-cure-bowl-game-predictions","tag-cure-bowl-picks","tag-florida","tag-florida-headlines","tag-florida-news","tag-old-dominion-monarchs","tag-old-dominion-south-florida-picks","tag-old-dominion-usf-odds","tag-old-dominion-usf-prediction","tag-south-florida-bulls"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/posts\/86859","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/comments?post=86859"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/posts\/86859\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/media\/86860"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/media?parent=86859"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/categories?post=86859"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-fl\/wp-json\/wp\/v2\/tags?post=86859"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}