At least six people were injured after a fire broke out at a building in the Bronx Wednesday afternoon, the FDNY said.

The department responded to a report of an explosion and fire at a five-story building on East 209th Street, between Decatur Avenue and Parkside Place in Norwood, just before 12:30 p.m. 

Firefighters discovered a blaze on the second and third floors of the building, according to the department. 

The FDNY said five civilians were hospitalized, two in critical condition and three in stable condition. A firefighter also sustained serious injuries, the department said. 

New York City Emergency Management said to expect smoke, traffic delays and emergency vehicles in the area. 

As of 1:50 p.m., the fire had escalated to a five-alarm blaze, the FDNY said.

This is a developing story. Check back for updates.