March 27, 2026, 3:12 p.m. ET

The Brooklyn Nets (17-56) and Los Angeles Lakers (47-26) meet at Crypto.com Arena on Friday. Tip-off from Los Angeles, California, is set for 10:30 p.m. ET. Let’s analyze NBA odds around the Nets vs. Lakers odds and make our expert NBA picks and predictions for the best bets.

Season series: Lakers lead 1-0

Brooklyn was handed a 109-106 loss by the Golden State Warriors on Wednesday, covering as a 12.5-point road underdog with the Under (218.5) cashing. The Nets were dominated 43-27 on the glass against the Warriors. The Nets have lost 9 straight and have been held under 100 points in 6 of those losses.

Los Angeles picked up a 137-130 win over the Indiana Pacers on Wednesday, failing to cover as an 8.5-point road favorite as the Over (241.5) was smashed. G Luka Doncic went off for 43 points while 3 other Lakers also scored over 20 in the win. The Lakers outscored the Pacers 70-54 in the paint.

The Lakers beat the Nets 125-109 on Feb. 3, covering as 8.5-point road favorites with the Over (222.5) cashing. F LeBron James led the Lakers with 25 points and Doncic chipped in 24 in the win. The Nets gave up 66 points in the paint and 31 fast-break points in the loss.

Watch the NBA on Fubo!Nets at Lakers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 3 p.m. ET.

Moneyline (ML): Nets +875 (bet $100 to win $875) | Lakers -1600 (bet $1,600 to win $100)Against the spread (ATS): Nets +15.5 (-102) | Lakers -15.5 (-118)Over/Under (O/U): 222.5 (O: -110 | U: -110)Nets at Lakers key injuries

Nets

C/F Noah Clowney (wrist) probableG Egor Demin (foot) outF Michael Porter Jr. (hamstring) outC Day’Ron Sharpe (thumb) outF Danny Wolf (ankle) out

Lakers

G Luka Doncic (hamstring) questionableF Rui Hachimura (calf) questionableG Marcus Smart (ankle) out

For most recent updates: Official NBA injury report.

Nets at Lakers picks and predictionsPrediction

Lakers 120, Nets 106

PASS.

The Lakers are the much better team, so covering as -1600 favorites here won’t be a problem. However, no team favored so heavily on the ML is worth the risk of betting on, so pass and bet on the spread and/or total instead.

LEAN NETS +15.5 (-102).

Brooklyn has covered the spread in 4 of its last 5 road games and is 3-1 ATS in its last 4 games overall. The Lakers, on the other hand, have dropped 3 straight ATS. The Nets are also 2-1 ATS in their last 3 overall against the Lakers and are 3-1 ATS in the last 4 matchups that took place in LA.

This is a LEAN because the Lakers are the much better team, and if Doncic can go here, this turns into a LEAN in favor of the Lakers.

BET OVER 222.5 (-110).

The Over has hit in 3 of LA’s last 5 overall and is 2-0 in its last 2 home games. The Over is also 38-35 for the Lakers this season. For Brooklyn, the Over is 2-1 in its last 3 road games. The Over has also hit in 3 of the last 4 matchups between these squads in LA and in 2 straight matchups overall.

If Doncic is able to play in this contest, the Over is essentially a lock.

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