A 36-year-old man in custody at a Bellevue Hospital jail unit died on Wednesday morning after he was found in medical distress.

Christopher Rodriguez was pronounced dead at about 8:39 a.m. at the Outposted Therapeutic Housing Unit at Bellevue, according to the Department of Correction, which runs the jail at the hospital. His death is at least the sixth in New York City jail custody this year.

“We are deeply saddened by the passing of Mr. Rodriguez. Our entire department mourns his loss,” Correction Commissioner Stanley Richards said in a statement.

Mayor Zohran Mamdani said in a statement that he was “heartbroken by the death earlier today of a New Yorker who was in city custody and receiving medical care” at the Bellevue unit, which he called “a facility dedicated to those with acute medical needs.”

The city opened the new facility in April after it had long been blocked by previous Mayor Eric Adams because of security concerns. Correction officials described the unit as a way to provide incarcerated people with more dignified treatment for their complex medical needs.

Rodriguez had been held since November of last year on several open assault cases in Queens and Brooklyn, according to Department of Correction records.

Police said he had most recently confronted a woman in the hallway of the Queens apartment building where he lived, hit her repeatedly with closed fists, grabbed her cellphone and smashed it, then cornered her with a knife. No injuries were reported.

He was separately indicted in the Bronx on a charge of second-degree assault, a felony, for allegedly striking a correction officer at Rikers Island in December, prosecutors said. That case was referred in April for a mental health competency evaluation, according to the Bronx district attorney’s office.

Darren Mack, co-director of the prisoner advocacy group Freedom Agenda, said in a statement that Rodriguez’s death, even at a therapeutic housing unit at Bellevue, underscored the need to close Rikers Island.

“We must move with urgency toward reducing the jail population, expanding community-based alternatives, closing Rikers, and building a city where incarceration is no longer the default response to poverty, mental health needs, and homelessness,” Mack said.

Lawyers for Rodriguez did not immediately return messages.

The city medical examiner will determine what caused Rodriguez’s death.