{"id":235911,"date":"2026-05-18T21:37:23","date_gmt":"2026-05-18T21:37:23","guid":{"rendered":"https:\/\/www.newsbeep.com\/us-ny\/235911\/"},"modified":"2026-05-18T21:37:23","modified_gmt":"2026-05-18T21:37:23","slug":"how-a-funding-pause-derailed-an-artificial-heart-for-babies","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us-ny\/235911\/","title":{"rendered":"How a Funding Pause Derailed an Artificial Heart for Babies"},"content":{"rendered":"<p class=\"css-ac37hb evys1bk0\">After the Trump Administration froze <a class=\"css-yywogo\" href=\"https:\/\/www.nytimes.com\/2025\/04\/08\/us\/politics\/cornell-northwestern-university-funds-trump.html\" title=\"\" rel=\"nofollow noopener\" target=\"_blank\">more than $1 billion in funding for Cornell<\/a> last April, James Antaki set his sights on retirement.<\/p>\n<p class=\"css-ac37hb evys1bk0\">For decades, Dr. Antaki, a biomedical engineer, had been building an artificial heart for babies and young children, a pump the size of a AA battery, and he was getting close. But with his research grants stopped, Dr. Antaki slowly drained his lab\u2019s rainy day funds, and he was forced to lay off all his staff. After months of waning optimism, he saw no real path forward.<\/p>\n<p class=\"css-ac37hb evys1bk0\">\u201cI\u2019m ready to pack up my bags, because what more can I do?\u201d Dr. Antaki remembered thinking.<\/p>\n<p class=\"css-ac37hb evys1bk0\">Then, right before Thanksgiving, the funding came back: \u201clike by magic,\u201d he said, adding, \u201cit was unbelievable.\u201d Dr. Antaki immediately called one of his former postdoctoral students, but the young scientist had already accepted a job elsewhere. Then came a university hiring freeze and a tangle of other problems that left Dr. Antaki trying to bring his laboratory back to life, before he could even think about resuming the research.<\/p>\n<p class=\"css-ac37hb evys1bk0\">\u201cI\u2019m embarrassed that we\u2019re not making any forward progress \u2014 or just baby steps,\u201d he said.<\/p>\n<p class=\"css-ac37hb evys1bk0\">Over the last year, the Trump administration has made <a class=\"css-yywogo\" href=\"https:\/\/www.nytimes.com\/interactive\/2025\/12\/02\/upshot\/trump-science-funding-cuts.html\" title=\"\" rel=\"nofollow noopener\" target=\"_blank\">deep cuts to the nation\u2019s science infrastructure<\/a>, forcing researchers to scale back their ambitions, delay critical work or abandon projects altogether. As universities have cut deals with the administration, Dr. Antaki is far from the only researcher whose funding was restored only after being forced to shut down for months.<\/p>\n<p class=\"css-ac37hb evys1bk0\">While restored funding can revive a project, it cannot buy back the continuity and momentum that science depends on. The unraveling of Dr. Antaki\u2019s laboratory illustrates not only how important public funding is for research but also how the damage from these cuts can endure long after the money returns.<\/p>\n<p>Why building a heart for babies is so hard<\/p>\n<p class=\"css-ac37hb evys1bk0\">Every year, there are about <a class=\"css-yywogo\" href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/circresaha.116.308996\" title=\"\" rel=\"noopener noreferrer nofollow\" target=\"_blank\">14,000 children hospitalized with heart failure<\/a> in the United States, but there are not many effective treatments.<\/p>\n<p class=\"css-ac37hb evys1bk0\">For teenagers, surgeons can jury-rig an adult artificial heart, said Dr. Emile Bacha, the chair of surgery at Columbia University Vagelos College of Physicians and Surgeons. But for younger children with severe cardiac conditions, surgeons rely on the Berlin Heart, an external pump that moves blood in and out of the body. Although the device can help keep these children alive as they wait for a heart transplant, it leaves them tethered and confined to an intensive care unit.<\/p>\n<p class=\"css-ac37hb evys1bk0\">Developed in the 1990s, the Berlin Heart also has a fairly high complication rate \u2014 most notably infections and strokes. These risks have only compounded with growing wait times for pediatric heart transplants, with fewer children dying in circumstances that allow organ donation and more patients surviving long enough to need them, Dr. Bacha said. So, some children die or become disabled before they can receive a new heart.<\/p>\n<p class=\"css-ac37hb evys1bk0\">The promise of a pediatric artificial heart is that it could be implanted inside sick children, supporting them with fewer complications and more freedom, and potentially eliminate the need for a transplant. But making this device a reality is an extraordinarily difficult engineering problem, said Dr. Joseph Turek, the chief of pediatric cardiac surgery at Duke University Medical Center. The pump needs to be small enough to fit inside a baby\u2019s chest, where the heart might be the size of a strawberry, and gentle enough to circulate blood without making it clot, since a newborn has about as much blood as a 12-ounce can of soda.<\/p>\n<p class=\"css-ac37hb evys1bk0\">\u201cThis is really hard research, so it\u2019s really been reserved for idealists,\u201d Dr. Bacha said.<\/p>\n<p class=\"css-ac37hb evys1bk0\">Because of the technical hurdles and the small market size, there is little financial incentive for private industry to get involved, Dr. Turek said. In an analysis of health technology companies, just <a class=\"css-yywogo\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11883554\/\" title=\"\" rel=\"noopener noreferrer nofollow\" target=\"_blank\">0.6 percent of seed funding<\/a> went to products focused on pediatrics. In many cases, federal support is the only thing keeping such research alive.<\/p>\n<p class=\"css-ac37hb evys1bk0\">\u201cIt won\u2019t happen otherwise; the dollars just don\u2019t add up,\u201d Dr. Turek said.<\/p>\n<p>What the funding cuts destroyed<\/p>\n<p class=\"css-ac37hb evys1bk0\">So much of research comes down to timing. Before Dr. Antaki\u2019s grants were frozen, he had the right team in place, time off from teaching, established partnerships and a 30-day animal study planned. But by the time the funding returned, all that momentum was gone.<\/p>\n<p class=\"css-ac37hb evys1bk0\">With the animal study, for example, Dr. Antaki intended to test his devices in sheep of just the right size to model a baby\u2019s circulatory system. When his funding disappeared, he needed to return these sheep to local farms, and in the fall, when the money returned, sheep of that size were no longer available. Similarly, Dr. Antaki needed a pediatric heart surgeon and anesthesiologist to find openings in their crowded schedules to make the two-hour drive to Ithaca and perform the operations \u2014 a process he would now have to start all over again. He was also counting on undergraduates to help monitor the animals after the operation, but now winter break was approaching, and most students were preparing to leave campus.<\/p>\n<p class=\"css-ac37hb evys1bk0\">Because this research is so specialized, there are only so many scientists who can move it along, Dr. Antaki said, and his old employees were not sitting around waiting to come back. The postdoctoral student he needed had moved on, and a backup candidate wasn\u2019t allowed to work in the United States because of the broad <a class=\"css-yywogo\" href=\"https:\/\/www.nytimes.com\/2025\/12\/16\/us\/politics\/trump-expanded-travel-ban.html\" title=\"\" rel=\"nofollow noopener\" target=\"_blank\">travel bans and restrictions<\/a> issued by the Trump Administration.<\/p>\n<p class=\"css-ac37hb evys1bk0\">\u201cI\u2019m struggling just to repopulate the team,\u201d Dr. Antaki said.<\/p>\n<p class=\"css-ac37hb evys1bk0\">In the meantime, Cornell imposed a hiring freeze, and he found himself buried in paperwork to get an exemption and restore agreements with outside partners, even as his teaching responsibilities had resumed. Before the funding pause, Dr. Antaki had secured a manufacturing partner to build his device, but after months of uncertainty, that company walked away. He has since had to search for a new manufacturer, reintroducing the project, working through the specifications and negotiating the contract.<\/p>\n<p class=\"css-ac37hb evys1bk0\">Although his funding was frozen for seven months, Dr. Antaki estimates the ordeal set his research back by at least twice as long. Harder to measure was the loss of trust. For years he had been telling clinical partners that the artificial heart was close, but the freeze turned anticipation into skepticism. In medicine, adopting any new technology requires a leap of faith, Dr. Turek said, and once momentum is broken, it becomes harder to persuade people to buy in again.<\/p>\n<p class=\"css-ac37hb evys1bk0\">With private industry largely uninterested in this kind of research, Dr. Antaki said he was grateful for government funding, despite the whiplash. \u201cThere\u2019s no point in being bitter or being angry or getting even,\u201d he said. \u201cI really have no choice but to push forward.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"After the Trump Administration froze more than $1 billion in funding for Cornell last April, James Antaki set&hellip;\n","protected":false},"author":2,"featured_media":235912,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[38],"tags":[3252,128,1692,6005,1452,31482,39989,31484,9,24,63,92343,129,131,130,1069],"class_list":["post-235911","post","type-post","status-publish","format-standard","has-post-thumbnail","category-the-bronx","tag-artificial","tag-bronx","tag-colleges-and-universities","tag-cornell-university","tag-donald-j","tag-federal-aid-us","tag-heart","tag-national-institutes-of-health","tag-new-york","tag-new-york-city","tag-nyc","tag-surgery-and-surgeons","tag-the-bronx","tag-the-bronx-headlines","tag-the-bronx-news","tag-trump"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/posts\/235911","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/comments?post=235911"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/posts\/235911\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/media\/235912"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/media?parent=235911"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/categories?post=235911"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/tags?post=235911"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}