{"id":330689,"date":"2026-08-27T01:31:12","date_gmt":"2026-08-27T01:31:12","guid":{"rendered":"https:\/\/www.newsbeep.com\/us-ny\/330689\/"},"modified":"2026-08-27T01:31:12","modified_gmt":"2026-08-27T01:31:12","slug":"nonprofit-biohub-software-firm-fundraise-up-lease-20k-sf-at-100-104-fifth-avenue-commercial-observer","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us-ny\/330689\/","title":{"rendered":"Nonprofit Biohub, Software Firm Fundraise Up Lease 20K SF at 100-104 Fifth Avenue \u2013 Commercial Observer"},"content":{"rendered":"<p>Two nonprofit-related tenants are moving to an office just west of Manhattan\u2019s Union Square.<\/p>\n<p>In the largest deal, the Chan Zuckerberg <a href=\"https:\/\/commercialobserver.com\/company\/biohub\/\" title=\"Biohub\" class=\"company-link\" rel=\"nofollow noopener\" target=\"_blank\">Biohub<\/a>, better known simply as Biohub, secured a 10,666-square-foot lease at <a href=\"https:\/\/commercialobserver.com\/company\/sovereign-partners\/\" title=\"Sovereign Partners\" class=\"company-link\" rel=\"nofollow noopener\" target=\"_blank\">Sovereign Partners<\/a>\u2019 100-104 Fifth Avenue, Commercial Observer has learned.\u00a0<\/p>\n<p>SEE ALSO: <a href=\"https:\/\/commercialobserver.com\/2026\/08\/nutter-lease-expansion-durst-5-grand-central-east\/\" rel=\"nofollow noopener\" target=\"_blank\">Law Firm Nutter Expands to 11K SF at Durst\u2019s 5 Grand Central East<\/a><\/p>\n<p>The nonprofit biomedical research organization will occupy the entire ninth floor of the 20-story tower at the southwest corner of Fifth Avenue and West 15th Street, according to sources. The building is one block west of Union Square.<\/p>\n<p>Biohub was founded in 2016 by Mark Zuckerberg and Priscilla Chan, with the goal to cure, prevent and manage human diseases. The company currently lists offices and a research laboratory at Columbia University\u2019s Studebaker Building at 615 West 131st Street. Sources said the move marks a relocation from a Biohub office near Union Square, but no address in the neighborhood was found.<\/p>\n<p>Biohub was represented by <a href=\"https:\/\/commercialobserver.com\/company\/newmark\/\" title=\"Newmark\" class=\"company-link\" rel=\"nofollow noopener\" target=\"_blank\">Newmark<\/a>\u2019s David Falk, Mike Courson and Dylan Weisman. Falk also represented Sovereign Partners alongside Daniel Levine and Paige Raisides. A spokesperson for Newmark did not respond to a request for comment on the transaction.\u00a0<\/p>\n<p>The nonprofit will be in good company at the Fifth Avenue office tower. <a href=\"https:\/\/commercialobserver.com\/company\/fundraise-up\/\" title=\"Fundraise Up\" class=\"company-link\" rel=\"nofollow noopener\" target=\"_blank\">Fundraise Up<\/a>, a fundraising platform designed for nonprofit organizations, has signed its own lease at the building.\u00a0<\/p>\n<p>Fundraise Up took 9,522 square feet across the entire seventh floor, in a relocation from 219 36th Street in Brooklyn\u2019s Industry City complex.<\/p>\n<p>The lease terms for both of the recent deals were not disclosed, but asking rents in the building range from $110 to $150 per square foot, according to the source.\u00a0<\/p>\n<p><a href=\"https:\/\/commercialobserver.com\/company\/cushman-wakefield\/\" title=\"Cushman &amp; Wakefield\" class=\"company-link\" rel=\"nofollow noopener\" target=\"_blank\">Cushman &amp; Wakefield<\/a>\u2019s David Hoffman, Sam Hoffman and Louden Sheehan negotiated the lease on behalf of Fundraise Up. The same Newmark team represented the landlord.\u00a0\u00a0<\/p>\n<p>Spokespeople for Newmark and Cushman &amp; Wakefield did not immediately respond to\u00a0 requests for comment.<\/p>\n<p>The two leases bring 100\u2013104 Fifth Avenue \u2014 which comprises two adjoining buildings \u2014 to 100 percent capacity. Other tenants include <a href=\"https:\/\/commercialobserver.com\/2022\/05\/fintech-firm-accrue-savings-leases-10k-sf-at-104-fifth-avenue\/\" rel=\"nofollow noopener\" target=\"_blank\">fintech firm<\/a> Accrue Savings and <a href=\"https:\/\/commercialobserver.com\/2023\/11\/battery-ventures-lease-fifth-avenue\/\" rel=\"nofollow noopener\" target=\"_blank\">investment firm<\/a> Battery Ventures.\u00a0<\/p>\n<p>Spokespeople for Sovereign Partners, Biohub and Fundraise Up did not immediately respond to requests for comment.<\/p>\n<p>Emily Davis can be reached at <a href=\"https:\/\/commercialobserver.com\/2026\/08\/biohub-fundraise-up-leases-100-104-fifth-avenue\/mailto:edavis@commercialobserver.com\" rel=\"nofollow noopener\" target=\"_blank\">edavis@commercialobserver.com<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"Two nonprofit-related tenants are moving to an office just west of Manhattan\u2019s Union Square. In the largest deal,&hellip;\n","protected":false},"author":2,"featured_media":330690,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36],"tags":[124504,124505,98,100,99,3624,70685,26047,124506,124442,2361,124507,48513,124508,9,24,63,124503,34484,124509,124510,124511],"class_list":["post-330689","post","type-post","status-publish","format-standard","has-post-thumbnail","category-brooklyn","tag-219-36th-street","tag-615-west-131st-street","tag-brooklyn","tag-brooklyn-headlines","tag-brooklyn-news","tag-channel","tag-daniel-levine","tag-david-falk","tag-david-hoffman","tag-dylan-weisman","tag-leases","tag-louden-sheehan","tag-mark-zuckerberg","tag-mike-courson","tag-new-york","tag-new-york-city","tag-nyc","tag-office-leases-100-104-fifth-avenue","tag-paige-raisides","tag-priscilla-chan","tag-sam-hoffman","tag-studebaker-building"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/posts\/330689","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/comments?post=330689"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/posts\/330689\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/media\/330690"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/media?parent=330689"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/categories?post=330689"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/tags?post=330689"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}