{"id":376276,"date":"2026-10-18T14:16:24","date_gmt":"2026-10-18T14:16:24","guid":{"rendered":"https:\/\/www.newsbeep.com\/us-ny\/376276\/"},"modified":"2026-10-18T14:16:24","modified_gmt":"2026-10-18T14:16:24","slug":"giants-vs-saints-prediction-nfl-week-6-picks-odds-best-bets-for-sunday","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us-ny\/376276\/","title":{"rendered":"Giants vs. Saints prediction: NFL Week 6 picks, odds, best bets for Sunday"},"content":{"rendered":"<p>\tGambling content 21+. The New York Post may receive an affiliate commission if you sign up through our links. Read our\u00a0<a href=\"https:\/\/nypost.com\/betting-editorial-standards\/\" target=\"_blank\" rel=\"noopener nofollow\">editorial standards<\/a>\u00a0for more information.<\/p>\n<p>The Giants can\u2019t wait to get back on the field after last week\u2019s overtime debacle against the Commanders. <\/p>\n<p>They have a chance to put it all behind them at home when they <a href=\"https:\/\/nypost.com\/video\/giants-vs-saints-will-big-blue-remain-unbeaten-at-metlife-blue-rush\/\" rel=\"nofollow noopener\" target=\"_blank\">host the Saints Sunday afternoon<\/a> at MetLife Stadium.<\/p>\n<p>Interestingly, the Giants <a href=\"https:\/\/nypost.com\/2026\/10\/13\/betting\/nfl-week-6-confidence-pool-rankings\/\" rel=\"nofollow noopener\" target=\"_blank\">are home underdogs<\/a> despite having the better regular season record than the Saints. The Giants are also 4-1 against the spread, including 2-0 as home dogs.<\/p>\n<p>Still, oddsmakers at <a href=\"https:\/\/nypost.com\/betting\/caesars-promo-code\/\" rel=\"nofollow noopener\" target=\"_blank\">Caesars Sportsbook<\/a> have the Saints as 1.5-point favorites with the Over\/Under sitting at 46 total points.<\/p>\n<p>Giants vs. Saints prediction<\/p>\n<p>The Giants may not be viewed as an actual contender, but they are still leading their division despite losing their starting quarterback in Week 2. <a href=\"https:\/\/nypost.com\/2026\/10\/14\/sports\/key-jameis-winston-trait-could-be-what-saves-this-giants-season\/\" rel=\"nofollow noopener\" target=\"_blank\">Jameis Winston has filled in admirably<\/a> as the backup and looks more comfortable with each start.<\/p>\n<p><img style=\"aspect-ratio:1.49926794;display:block\" loading=\"lazy\" decoding=\"async\"   data-modal-image=\"41380082\" width=\"885\" height=\"590\" src=\"https:\/\/www.newsbeep.com\/us-ny\/wp-content\/uploads\/2026\/10\/pressured-cardinals-linebacker-jack-gibbens-143779305.jpg\" alt=\"New York Giants quarterback Jameis Winston (19) throws a pass as Arizona Cardinals linebacker Jack Gibbens (50) pressures him during an NFL game.\" class=\"wp-image-41380082\"\/>New York Giants quarterback Jameis Winston (19) throws a touchdown pass to wide receiver Malachi Fields (88) as Arizona Cardinals linebacker Jack Gibbens (50) pressures him during the second quarter of an NFL football game in East Rutherford, N.J., Sunday, Oct. 4, 2026. Bill Kostroun for NY Post<\/p>\n<p>He still makes some decisions that likely have his coaches holding their collective breath. However, the G-Men were dead in the water last week before Winston turned things around for them in the fourth quarter. He also engineered two drives in a wet and sloppy overtime that ended in a missed field goal and lost fumble by a gloveless Cam Skattebo.<\/p>\n<p>Flaws and all, this offense still looks like it can produce with Winston under center.<\/p>\n<p>The same can be said about the Saints, too. <\/p>\n<p>New Orleans is just 1-4 on the season and coming off its lowest scoring game of the season, but the context is important. The Saints took on the Vikings, arguably the <a href=\"https:\/\/nypost.com\/betting\/best-nfl-betting-sites\/\" rel=\"nofollow noopener\" target=\"_blank\">NFL<\/a>\u2018s best defensive unit top to bottom.<\/p>\n<p>Tyler Shough was seeing ghosts against the Vikes. Still, he has been slinging the ball like one of the best passers this season.<\/p>\n<p>Betting on the NFL? <\/p>\n<p>Both defenses in this matchup can be exploited. They each blitz at high rates, but force opposing quarterbacks to hurry out of the pocket at rates that rank near the bottom of the league. <\/p>\n<p>There will be plenty of opportunities to score in this one, and I like the Over at 46.<\/p>\n<p>The Pick: Over 46 (-110, Caesars)<\/p>\n<p>Why Trust New York Post Betting<\/p>\n<p>Malik Smith has been immersed in the sports betting industry since 2017. He\u2019s a data nerd with a particular focus on the NBA and combat sports. He spends his weeknights in the winter looking for edges on plus-money NBA player props.<\/p>\n","protected":false},"excerpt":{"rendered":"Gambling content 21+. The New York Post may receive an affiliate commission if you sign up through our&hellip;\n","protected":false},"author":2,"featured_media":376277,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[6112,2682,9,2683,11,10,22,7453,319,6115,7454],"class_list":["post-376276","post","type-post","status-publish","format-standard","has-post-thumbnail","category-new-york","tag-betting","tag-new-orleans-saints","tag-new-york","tag-new-york-giants","tag-new-york-headlines","tag-new-york-news","tag-nfl","tag-nfl-betting","tag-sports","tag-sports-betting","tag-sports-picks"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/posts\/376276","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/comments?post=376276"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/posts\/376276\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/media\/376277"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/media?parent=376276"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/categories?post=376276"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-ny\/wp-json\/wp\/v2\/tags?post=376276"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}