Updated Dec. 12, 2025, 10:01 a.m. ET

The Indiana Pacers (6-18) and Philadelphia 76ers (13-10) meet Friday at Xfinity Mobile Arena in Philadelphia, Pennsylvania. Tip-off is set for 7 p.m. ET. Let’s analyze BetMGM Sportsbook’s NBA odds around the Pacers vs. 76ers odds and make our expert NBA picks and predictions for the best bets.

2024-25 season series: Pacers won 3-1

The Pacers beat the Sacramento Kings 116-105 Monday, covering as a 4-point home favorite with the Under (232) cashing. G Andrew Nembhard led all scorers with 28 points on 10-for-18 shooting. After going 2-16 over their first 18 games, the Pacers have shown signs of life, going 4-2 in their last 6 while covering in each win. They are 13-11 against the spread (ATS) this season.

The 76ers lost to the Los Angeles Lakers 112-108 Sunday, failing to cover as a 2.5-point home underdog with the Under (234) hitting. Philadelphia was led by G Tyrese Maxey, who scored 28 points on 11-for-24 shooting. The loss also snapped the 76ers’ 3-game winning streak. They’ve gone 4-2 straight up and 3-3 ATS in their last 6 games. Philadelphia is 13-9-1 ATS this season.

Watch the NBA on Fubo!Pacers at 76ers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:58 a.m. ET.

Moneyline (ML): Pacers +240 (bet $100 to win $240) | 76ers -300 (bet $300 to win $100)Against the spread: Pacers +7.5 (-115) | 76ers -7.5 (-105)Over/Under (O/U): 226.5 (O: -105 | U: -115)Pacers at 76ers key injuries

Pacers

G Tyrese Haliburton (Achilles) out for seasonG Quenton Jackson (hamstring) questionableG Aaron Nesmith (knee) outF Obi Toppin (foot) out

76ers

C Joel Embiid (knee) probableG Tyrese Maxey (illness) probableG Kelly Oubre Jr. (knee) out

For most recent updates: Official NBA injury report.

Pacers at 76ers picks and predictionsPrediction

76ers 116, Pacers 110

PASS.

There isn’t a worthwhile moneyline option. The 76ers (-300) are relatively healthy and should win at home, but that price makes the play easy to pass on.

BET PACERS +7.5 (-115).

The 76ers have been atrocious at covering at home. They’re just 1-7 ATS over their last 8 home games and 1-4 ATS as a home favorite. Philadelphia’s offense has also gone cold, scoring 116 or fewer in 3 straight.

The Pacers have found a rhythm, especially on offense, putting up at least 116 points in 4 straight games. They’re 8-2 ATS in their last 10 and 3-0 ATS in their road games over that span. Given those trends, back PACERS +7.5 (-115).

BET UNDER 226.5 (-115).

Both teams are trending toward the Under. The Pacers have gone Under in 5 of their last 7 contests, largely because of their rock-solid defense. They’ve allowed 105 or fewer points in each of those Under results.

The 76ers have gone Under in 4 straight and have also tightened things up defensively, giving up more than 112 points in just 1 of their last 6 outings. Take UNDER 226.5 (-115).

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