PITTSBURGH, PA — A Pittsburgh native will headline the first show at the city’s newest concert venue opening later this year.

Wiz Khalifa will perform on Oct. 2 at Citizens Live at the Wylie in the Lower Hill District on a portion of the former Civic Arena site.

The new venue, which will be operated by Live Nation, can hold as many as 4,000 people.

“We’re thrilled to begin announcing the first shows coming to Citizens Live at the Wylie,” Tom Loudermilk, Live Nation’s Pittsburgh market president, said in a statement.

“This is a special venue that will deliver unforgettable live music. It will bring an incredible mix of artists to the Lower Hill District, including Pittsburgh icons and artists who have never headlined here before.”

The initial lineup at the venue includes musical and comedy acts:

Oct. 2: Wiz Khalifa Oct. 3: Styx Oct. 6: Two Door Cinema Club Oct. 7: Freya Skye Oct. 8: Matt Mathews Oct. 9: Chelsea Handler Oct. 16: Boyz II Men Oct. 20: Tedeschi Trucks Band Oct. 27: The Living Tombstone Oct. 31: Aries Spears Nov. 2: GloRilla Nov. 6: Sting Nov. 15: Wyatt Flores Dec. 2: Stephen Wilson Jr. Dec. 3: Sabaton Jan. 16: Slappers N Bangers vs. Union