Boston will be looking to slow down the 76ers backcourt duo of Tyrese Maxey and VJ Edgecombe, who combined to torch the Celtics for 74 points in a Philadelphia win on opening night.

The 76ers stayed hot after that victory at TD Garden, winning their first four games to enter Friday’s matchup unbeaten.

Tip-off in Philadelphia is set for 7 p.m. The game will be streamed on Amazon Prime.

When: Friday, 7 p.m.

Where: Xfinity Mobile Arena, Philadelphia

TV, radio: Amazon, WBZ-FM 98.5

Line: Philadelphia -1.5. O/U: 234.5.

CELTICS

Season record: 2-3. vs. spread: 2-3. Over/under: 2-3

Last 10 games: 4-6. vs. spread: 4-6. Over/under: 4-6

76ERS

Season record: 4-0. vs. spread: 2-2. Over/under: 4-0

Last 10 games: 5-5. vs. spread: 4-5, 1 push. Over/under: 7-3

TEAM STATISTICS

Points per game: Boston 114.2, Philadelphia 129.3

Points allowed per game: Boston 107.2, Philadelphia 123.8

Field goal percentage: Boston .446, Philadelphia .469

Opponent field goal percentage: Boston .400, Philadelphia .488

3-point percentage: Boston .331, Philadelphia .419

Opponent 3-point percentage: Boston .327, Philadelphia .340

Stat of the day: Maxey is off to a sizzling start, averaging 37.5 points and 8.3 assists while knocking down 47.4% of his 3-pointers.

Notes: The Celtics rolled over the Cavaliers 125-105 on Wednesday as Jaylen Brown scored 30 points, Sam Hauser added 21, and three other Celtics registered a double-double. “Five games in; we’ve got 77 left,” Boston coach Joe Mazzulla said. “We’ve got to do it every night. … But there was a lot of minutes over the last two, three games where [I’ve thought], ’This is who we have to be.’” … Philadelphia rallied for a 139-134 overtime win Tuesday over the host Wizards. “We don’t want this to become a habit, but it does say that we’re tough,” Maxey said. … Former MVP Joel Embiid is still nursing a knee injury that is limiting him to about 20 minutes per game. However, he has made the most of those minutes in his last two outings, including a 25-point performance against the Wizards. “it’s extremely annoying,” Embiid said of the minutes restriction, “but as long as we win, I’m happy. When we lose and I feel like I could have done something, then I might feel some type of way. We’re winning. So, I don’t really care.”

Amin Touri can be reached at amin.touri@globe.com.