PITTSBURGH — Ryan Conwell hit five 3-pointers and scored 24 points, and all five Louisville starters scored in double figures as the 20th-ranked Cardinals routed Pittsburgh 100-59 on Saturday night.

J’Vonne Hadley scored 17 points, Sanadra Fru and Adrian Wooley each added 12 and Isaac McKneeley had 11 as Louisville (13-5, 2-4 ACC) shot 63.2% (36 of 57) from the field and 51.7% (15 of 29) from 3-point range. The Cardinals also held a 35-23 rebounding edge.

Louisville (13-5, 2-4 ACC) scored the first 13 points on its way to a 53-22 halftime lead. McKneely made three 3-pointers in the Cardinals’ game-opening run. Louisville outscored Pitt 18-1 later in the first half to extend its lead to 39-8.

Louisville won for just the second time in five games and bounced back after losing 79-70 to No. 16 Virginia on Tuesday. The Cardinals shot a season-worst 35.8% overall and 26.3% on 3-pointers.

Brandin Cummings scored 11 points off the bench for Pitt (8-10, 1-4), which has lost four of its last five games. The Panthers shot 38.2% (21 of 55).

Mikel Brown Jr., Louisville’s five-star freshman guard, missed his ninth straight game. Key reserve Khani Rooks sat out consecutive games because of illness.

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Louisville: Host Virginia Tech on Saturday.

Louisville center Aly Khalifa (15) looks to pass with Pittsburgh...

Louisville center Aly Khalifa (15) looks to pass with Pittsburgh forward Roman Siulepa (13) defending during the first half of an NCAA college basketball game in Pittsburgh, Saturday, Jan. 17, 2026. Credit: AP/Gene J. Puskar

Pittsburgh: At Boston College on Wednesday night.