{"id":13697,"date":"2025-10-24T14:13:25","date_gmt":"2025-10-24T14:13:25","guid":{"rendered":"https:\/\/www.newsbeep.com\/us-pa\/13697\/"},"modified":"2025-10-24T14:13:25","modified_gmt":"2025-10-24T14:13:25","slug":"updates-on-the-pancreatic-cancer-vaccine-at-lvhn-the-regions-only-clinical-trial-site","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us-pa\/13697\/","title":{"rendered":"Updates on the Pancreatic Cancer Vaccine at LVHN, the Region\u2019s Only Clinical Trial Site"},"content":{"rendered":"<p>After a patient undergoes surgery, scientists analyze the unique mutations in that individual\u2019s tumor. The patient\u2019s immune system learns to detect those specific cancer mutations and create a lasting immune response that can prevent the cancer from coming back.<\/p>\n<p>\u201cThe idea is to reprogram the tumor microenvironment,\u201d Dr. Nair says. \u201cThe vaccine sensitizes the patient\u2019s T cells to the specific KRAS mutation that is present in their pancreatic cancer. This allows the body to mount an immune response against the cancer.\u201d\u00a0<\/p>\n<p>\u201cEarly clinical trials have shown remarkably promising results,\u201d says <a href=\"https:\/\/www.lvhn.org\/doctors\/maged-khalil\" rel=\"nofollow noopener\" target=\"_blank\">Maged Khalil, MD<\/a>, Associate Director of Research with the Cancer Institute. \u201cMany patients developed robust immune responses, and some have remained cancer-free well beyond the expected time frame for recurrence.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"After a patient undergoes surgery, scientists analyze the unique mutations in that individual\u2019s tumor. The patient\u2019s immune system&hellip;\n","protected":false},"author":2,"featured_media":13698,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14],"tags":[153,155,154],"class_list":["post-13697","post","type-post","status-publish","format-standard","has-post-thumbnail","category-bethlehem","tag-bethlehem","tag-bethlehem-headlines","tag-bethlehem-news"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us-pa\/wp-json\/wp\/v2\/posts\/13697","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us-pa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us-pa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-pa\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-pa\/wp-json\/wp\/v2\/comments?post=13697"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us-pa\/wp-json\/wp\/v2\/posts\/13697\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-pa\/wp-json\/wp\/v2\/media\/13698"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us-pa\/wp-json\/wp\/v2\/media?parent=13697"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-pa\/wp-json\/wp\/v2\/categories?post=13697"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us-pa\/wp-json\/wp\/v2\/tags?post=13697"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}