Jan. 14, 2026, 2:56 p.m. ET

The TCU Horned Frogs (11-5, 1-2 Big 12) and No. 11 BYU Cougars (15-1, 3-0) meet Wednesday. Tip-off from Marriott Center in Provo, Utah, is scheduled for 11 p.m. ET (ESPN2). Let’s analyze BetMGM Sportsbook’s NCAA basketball odds around the TCU vs. BYU odds and make our expert college basketball picks and predictions for the best bets.

These teams have met twice as Big 12 combatants, once on March 2, 2024, and the other Jan. 11 of last year, with the home team winning straight up (SU) and against the spread (ATS) both times. The Over-Under split 1-1. In their first meeting as Big 12 combatants, in Provo in 2024, BYU won 87-75 as a 6.5-point favorite as the Over (155) cashed.

TCU was roughed up at home by No. 1 Arizona on Saturday, falling 86-73 as a 7.5-point underdog, snapping a 3-game cover streak. G Tanner Toolson supplied a team-best 20 points off the bench while adding 6 boards and 3 made 3-pointers as the Over (157.5) cashed. TCU has lost back-to-back games for the first time this season while the Over is 3-1 in the Horned Frogs’ past 4 games.

On Saturday, BYU topped rival Utah on the road, 89-84, though the Utes covered as 14.5-point underdogs in Salt Lake City and the Over (168.5) cashed. The Cougars had 3 scores with at least 20 points, as G Richie Saunders had 24 points and 14 rebounds, G Robert Wright III had 23 points with 6 assists and a pair of treys, and F A.J. Dybantsa had 20 points on 6-of-11 shooting.

The Cougars have won 12 in a row since their only setback on a neutral floor against then-No. 3 UConn back on Nov. 15. The Cougars are just 2-3 ATS in their past 5 games, though, while the Over is 5-1 in their past 6 contests.

– Rankings: USA TODAY Sports Coaches Poll

Watch NCAA basketball on Fubo!TCU at BYU odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:51 a.m. ET.

Moneyline (ML): TCU +650 (bet $100 to win $650) | BYU -1000 (bet $1,000 to win $100)Against the spread: TCU +13.5 (-118) | BYU -13.5 (-102)Over/Under (O/U): 158.5 (O: -110 | U: -110)TCU at BYU picks and predictionsPrediction

BYU 89, TCU 74

BYU (-1000) will cost you 10 times your potential return, and that’s way too much risk for not enough reward. There is never a reason to bet such a heavy favorite straight up, and it’s a losing betting strategy over the long term.

PASS.

BYU -13.5 (-102) is a good play back at home. It cashed in its first conference game on the home hardwood with the Cougars paddling Arizona State 104-76 as a 16.5-point favorite last Wednesday. The Cougars are 4-3 ATS in 7 games at home.

TCU has dropped back-to-back games and is 3-4 ATS in its past 7 games. The Horned Frogs covered at Kansas on Jan. 6 in their first true road game, falling 104-100 in overtime while covering as a 6.5-point underdog.

OVER 158.5 (-110) might be the best play on the board in this Big 12 clash.

The Over has hit in 3 of the past 4 games for TCU, with the Horned Frogs hitting triple digits on offense in 2 of those outings.

For BYU, the Over has cashed in 5 of the past 6 games, with the Cougars piling up 83 or more points in 7 consecutive outings. The Cougars have averaged 92.0 PPG in 3 conference games while allowing 77.7 PPG in those Big 12 outings.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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