Updated March 25, 2026, 11:20 p.m. ET

The Texas Longhorns (21-14) and No. 13 Purdue Boilermakers (29-8) battle Thursday in NCAA Tournament action in San Jose, California. The West Region Sweet 16 matchup at the SAP Center at San Jose will tip off at 7:10 p.m. ET (CBS). Let’s analyze NCAA basketball odds around the Texas vs. Purdue odds and make our expert college basketball picks and predictions for the best bets.

Texas, the West No. 11 seed after a 68-66 First 4 win over the NC State Wolfpacks, earned bracket wins over the No. 6 BYU Cougars (79-71) and the 3-seed Gonzaga Bulldogs. In Saturday’s triumph over -6.5 Gonzaga (74-68, Under 146.5), the Longhorns yielded just 4 made triples. In 2 tourney games, UT’s perimeter defense has held opposing 3-point shooters to a lowly 21.1% mark.

No. 2-seed Purdue went 1-3 over its last 4 regular-season games, but the Boilermakers then swept their way to a triumph in the Big Ten Tournament in Chicago. They rode that momentum to first-week tournament wins over the 15-seed Queens Royals (104-71) and the No. 7 Miami Hurricanes. In the second-round game, -7.5 Purdue defeated the Hurricanes 79-69 (Over 146.5). Purdue has won 3 in a row against the number.

Texas leads the all-time series 4-2. The teams last met in the 2022 NCAA Tournament. The -3 Boilermakers, a 3-seed, defeated the 6-seeded Longhorns 81-71 in an East Region second-round game.

– Rankings: USA TODAY Sports Coaches Poll

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Watch NCAA basketball on Fubo!Texas vs. Purdue odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 11:04 p.m. ET.

Moneyline (ML): Texas +270 (bet $100 to win $270) | Purdue -345 (bet $345 to win $100)Against the spread (ATS): Texas +7.5 (-115) | Purdue -7.5 (-105)Over/Under (O/U): 147.5 (O: -115 | U: -105)

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Texas vs. Purdue picks and predictionsPrediction

Purdue 80, Texas 70

No interest; PASS.

Since 2021, Purdue has gone 12-3 ATS in 15 NCAA Tournament games.

Both sides had piled up some ATS losses late in the regular season, but from an advanced metrics standpoint, the Boilermakers missteps were of a variety much closer to their normal high level of play. And while Texas has performed well of late, it as logged some shaky games that are not too far back in the rearview mirror.

UT is the current BartTorvik, No. 40. Since Feb. 14, Purdue has clocked a 21-point win over Torvik No. 23 the Iowa Hawkeyes, a 29-point win over Torvik No. 32 Indiana Hoosiers, a 7-point win over Torvik No. 25 UCLA Bruins and a 10-point victory over Torvik No. 33 Miami Hurricanes. That all bodes well for the Boilermakers covering this one.

Purdue is an excellent shooting team, and its offensive-end efficiency is buoyed by avoiding turnovers and working hard to crank out second-chance point off rebounds. On defense, Purdue walls off the paint and does so without fouling. And Texas can’t be at its best without creating a slew of trips to the charity stripe.

The Boilermakers have been on a roll with their second-half production. Look for Purdue to control this one and get it to the barn somewhere in the neighborhood of a 9-to-12-point differential.

TAKE PURDUE -7.5 (-105).

The Over is 9-3 across Purdue’s last 12 games. When Texas has played with 4-or-more days’ rest, the Over has gone 6-2.

Both sides play slow. Purdue is bottom-quartile deliberate. But Texas figures to be playing from behind in this match-up, and late in the regular season the Longhorns had been speeding things up. We should expect 3s to contribute enough of a scoring share that 150 gets tipped.

BACK THE OVER 147.5 (-115).

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