April 4, 2026, 11:39 a.m. ET

The San Antonio Spurs (59-18) and Denver Nuggets (49-28) meet Saturday at 3 p.m. ET from Ball Arena in Denver, Colorado (Prime Video). Let’s analyze NBA odds around the Spurs vs. Nuggets odds and make our expert NBA picks and predictions for the best bets.

Season series: Tied 1-1

The Spurs beat the LA Clippers 118-99 Thursday, covering as a slight 2.5-point road underdog with the Under (232.5) cashing. San Antonio has been scorching hot, winning 11 straight and covering in 6 of those. It is 42-33-2 against the spread (ATS) on the season and sits second in the Western Conference, 10 games ahead of the fourth-place Nuggets.

The Nuggets took down the Utah Jazz 130-117 Wednesday, failing to cover as a massive 17-point road favorite. The Under (249.5) hit. Denver has ripped off 7 straight wins, scoring at least 125 points in 5 of those contests. But the Nuggets are 2-5 ATS in their last 7 games and 41-36 ATS on the season. They’re 1 game behind the Lakers, who are third in the Western Conference.

The road team has won outright and covered the spread in each of the two meetings between these teams this season.

Watch the NBA on Fubo!Spurs at Nuggets odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:30 a.m. ET.

Moneyline (ML): Spurs -135 (bet $135 to win $100) | Nuggets +110 (bet $100 to win $110)Against the spread (ATS): Spurs -1.5 (-115) | Nuggets +1.5 (-105)Over/Under (O/U): 243.5 (O: -110 | U: -110)Spurs at Nuggets key injuries

Spurs

Nuggets

G Tim Hardaway Jr. (knee) probableF Peyton Watson (hamstring) out

For most recent updates: Official NBA injury report.

Spurs at Nuggets picks and predictionsPrediction

Spurs 125, Nuggets 122

PASS.

While the odds present value for both the Spurs (-135) and Nuggets (+110), the only side worth taking is the home team on the moneyline. Given the predicted outcome, avoid that play.

BET SPURS -1.5 (-115).

The Spurs are rolling and they’re performing at a high level on the road. San Antonio has covered 5 of its last 6 away games and sits 23-16-1 ATS on the road this season, the sixth-best covering rate in the NBA.

The Nuggets beat the Spurs by 5 points on the road on March 12, but San Antonio was short star C Victor Wembanyama. He’s missed both matchups this season and should present a challenge for C Nikola Jokic. Denver is 1-3 ATS in its last 4 games with a single-digit spread.

BET OVER 243.5 (-110).

Both teams have ultra-efficient offenses and should have their way Saturday afternoon.

San Antonio has scored at least 123 points in 6 of its last 7 games. Denver has topped 130 points in 3 of its last 4 games. In the previous 2 matchups between these sides, the Over hit in both.

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