Oct 27, 2025, 06:00 PM ET
There are three ranked matchups this weekend, as the path to the College Football Playoff begins to take shape. At noon on ABC, No. 9 Vanderbilt take on No. 20 Texas and at 7:30, the No. 18 Oklahoma face No. 14 Tennessee. Vanderbilt’s ranking is the highest since they reached No. 7 in 1937, according to ESPN Research.
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ESPN College Gameday will be in Salt Lake City for the final ranked matchup of the night, as Big 12 rivals No. 17 Cincinnati square off with No. 20 Utah at 10:15 p.m. The Bearcats haven’t been ranked this high since 2021, the year they qualified for the Playoff.
Elsewhere on the schedule, No. 1 Ohio State is back in action after their bye, hosting an unranked Penn State. West Virginia fly south to take on No. 22 Houston, who are ranked for the first time since joining the Big 12.
No. 5 Georgia and No. 8 Georgia Tech are ranked in the top 10 for consecutive weeks for the first time since 1999.
All times Eastern. For latest lines, go to ESPN BET

 No. 25 Memphis -13.5 at Rice
No. 25 Memphis -13.5 at Rice
Friday, 7 p.m., ESPN2
Records: Memphis 7-1, 1-0 vs. AP teams; Rice 4-4, 0-0 vs. AP teams
Opening Line: Memphis -13.5, O/U 54.5
Money line: Memphis (-650); Rice (+425)
Over/Under: 49.5 (O -110, U -110)
FPI Projection Memphis by 18.8 points with a 92% probability to win game outright

 Penn State at No. 1 Ohio State -20.5
Penn State at No. 1 Ohio State -20.5
Saturday, Noon, FOX
Records: Penn State 3-4, 0-1 vs. AP teams; Ohio State 7-0, 2-0 vs. AP teams
Opening Line: Ohio State -20.5, O/U 43.5
Money line: Penn State (+1100); Ohio State (-2500)
Over/Under: 43.5 (O -110, U -110)
FPI Projection Ohio State by 14.7 points with a 88% probability to win game outright

 No. 9 Vanderbilt at No. 20 Texas -1.5
No. 9 Vanderbilt at No. 20 Texas -1.5
Saturday, Noon, ABC
Records: Vanderbilt 7-1, 3-1 vs. AP teams; Texas 6-2, 1-1 vs. AP teams
Opening Line: Texas -2.5, O/U 45.5
Money line: Vanderbilt (+105); Texas (-125)
Over/Under: 44.5 (O -105, U -115)
FPI Projection Texas by 5.7 points with a 71% probability to win game outright

 No. 10 Miami -11.5 at SMU
No. 10 Miami -11.5 at SMU
Saturday, Noon, ESPN
Records: Miami 6-1, 3-0 vs. AP teams; SMU 5-3, 0-0 vs. AP teams
Opening Line: Miami -10.5, O/U 50.5
Money line: Miami (-425); SMU (+320)
Over/Under: 50.5 (O -110, U -110)
FPI Projection Miami by 5.3 points with a 70% probability to win game outright

 West Virginia at No. 22 Houston -14.5
West Virginia at No. 22 Houston -14.5
Saturday, Noon, FS1
Records: West Virginia 2-6, 0-1 vs. AP teams; Houston 7-1, 1-1 vs. AP teams
Opening Line: Houston -15.5, O/U 49.5
Money line: West Virginia (+475); Houston (-750)
Over/Under: 49.5 (O -110, U -110)
FPI Projection Houston by 10 points with a 81% probability to win game outright

 No. 16 Louisville -10.5 at Virginia Tech
No. 16 Louisville -10.5 at Virginia Tech
Saturday, 3 p.m., The CW Network
Records: Louisville 6-1, 1-1 vs. AP teams; Virginia Tech 3-5, 0-2 vs. AP teams
Opening Line: Louisville -10.5, O/U 53.5
Money line: Louisville (-425); Virginia Tech (+320)
Over/Under: 54.5 (O -105, U -115)
FPI Projection Louisville by 6.4 points with a 74% probability to win game outright

 No. 2 Indiana -22.5 at Maryland
No. 2 Indiana -22.5 at Maryland
Saturday, 3:30 p.m., CBS
Records: Indiana 8-0, 2-0 vs. AP teams; Maryland 4-3, 0-0 vs. AP teams
Opening Line: Indiana -21.5, O/U 51.5
Money line: Indiana (-3000); Maryland (+1200)
Over/Under: 50.5 (O -110, U -110)
FPI Projection Indiana by 17.1 points with a 90% probability to win game outright

 No. 5 Georgia -7.5 at Florida
No. 5 Georgia -7.5 at Florida
Saturday, 3:30 p.m., ABC
Records: Georgia 6-1, 2-1 vs. AP teams; Florida 3-4, 1-3 vs. AP teams
Opening Line: Georgia -7.5, O/U 50.5
Money line: Georgia (-300); Florida (+250)
Over/Under: 50.5 (O -110, U -110)
FPI Projection Georgia by 9.3 points with a 80% probability to win game outright

 No. 12 Notre Dame -29.5 at Boston College
No. 12 Notre Dame -29.5 at Boston College
Saturday, 3:30 p.m., ESPN
Records: Notre Dame 5-2, 1-2 vs. AP teams; Boston College 1-7, 0-1 vs. AP teams
Opening Line: Notre Dame -29.5, O/U 58.5
Money line: Notre Dame (-7500); Boston College (+2000)
Over/Under: 55.5 (O -115, U -105)
FPI Projection Notre Dame by 29.3 points with a 97% probability to win game outright

 No. 13 Texas Tech -7.5 at Kansas State
No. 13 Texas Tech -7.5 at Kansas State
Saturday, 3:30 p.m., FOX
Records: Texas Tech 7-1, 1-0 vs. AP teams; Kansas State 4-4, 0-1 vs. AP teams
Opening Line: Texas Tech -6.5, O/U 53.5
Money line: Texas Tech (-275); Kansas State (+225)
Over/Under: 53.5 (O -110, U -110)
FPI Projection Texas Tech by 3.6 points with a 65% probability to win game outright

 No. 15 Virginia -4.5 at California
No. 15 Virginia -4.5 at California
Saturday, 3:45 p.m., ESPN2
Records: Virginia 7-1, 1-0 vs. AP teams; California 5-3, 0-0 vs. AP teams
Opening Line: Virginia -3.5, O/U 54.5
Money line: Virginia (-175); California (+150)
Over/Under: 53.5 (O -115, U -105)
FPI Projection Virginia by 4.7 points with a 68% probability to win game outright

 South Carolina at No. 7 Ole Miss -13.5
South Carolina at No. 7 Ole Miss -13.5
Saturday, 7 p.m., ESPN
Records: South Carolina 3-5, 0-4 vs. AP teams; Ole Miss 7-1, 2-1 vs. AP teams
Opening Line: Ole Miss -14.5, O/U 53.5
Money line: South Carolina (+425); Ole Miss (-650)
Over/Under: 54.5 (O -110, U -110)
FPI Projection Ole Miss by 9.9 points with a 81% probability to win game outright

 Purdue at No. 21 Michigan -20.5
Purdue at No. 21 Michigan -20.5
Saturday, 7 p.m., BTN
Records: Purdue 2-6, 0-2 vs. AP teams; Michigan 6-2, 0-1 vs. AP teams
Opening Line: Michigan -21.5, O/U 50.5
Money line: Purdue (+1100); Michigan (-2500)
Over/Under: 49.5 (O -105, U -115)
FPI Projection Michigan by 21.6 points with a 94% probability to win game outright

 No. 8 Georgia Tech -6.5 at NC State
No. 8 Georgia Tech -6.5 at NC State
Saturday, 7:30 p.m., ESPN2
Records: Georgia Tech 8-0, 1-0 vs. AP teams; NC State 4-4, 0-1 vs. AP teams
Opening Line: Georgia Tech -6.5, O/U 57.5
Money line: Georgia Tech (-195); NC State (+165)
Over/Under: 57.5 (O -110, U -110)
FPI Projection Georgia Tech by 5.6 points with a 71% probability to win game outright

 No. 18 Oklahoma at No. 14 Tennessee -2.5
No. 18 Oklahoma at No. 14 Tennessee -2.5
Saturday, 7:30 p.m., ABC
Records: Oklahoma 6-2, 2-1 vs. AP teams; Tennessee 6-2, 0-2 vs. AP teams
Opening Line: Tennessee -3.5, O/U 56.5
Money line: Oklahoma (+120); Tennessee (-140)
Over/Under: 57.5 (O -105, U -115)
FPI Projection Tennessee by 3.3 points with a 63% probability to win game outright

 No. 23 USC -6.5 at Nebraska
No. 23 USC -6.5 at Nebraska
Saturday, 7:30 p.m., NBC
Records: USC 5-2, 1-2 vs. AP teams; Nebraska 6-2, 0-1 vs. AP teams
Opening Line: USC -6.5, O/U 58.5
Money line: USC (-250); Nebraska (+210)
Over/Under: 59.5 (O -110, U -110)
FPI Projection USC by 5.9 points with a 72% probability to win game outright

 No. 17 Cincinnati at No. 24 Utah -8.5
No. 17 Cincinnati at No. 24 Utah -8.5
Saturday, 10:15 p.m., ESPN
Records: Cincinnati 7-1, 1-0 vs. AP teams; Utah 6-2, 1-2 vs. AP teams
Opening Line: Utah -7.5, O/U 57.5
Money line: Cincinnati (+250); Utah (-300)
Over/Under: 56.5 (O -110, U -110)
FPI Projection Utah by 9.7 points with a 81% probability to win game outright
 
				 
				
	
