The Houston Astros are scheduled to open the 2027 season at home against their in-state rival, provided baseball’s anticipated offseason labor dispute doesn’t spill into the regular season.

Major League Baseball released a schedule for 2027 on Thursday with opening day set for March 25. The Astros are scheduled to host the Texas Rangers in a three-game series March 25-27 and the Red Sox from March 29-31.

It would mark the third time the Astros and Rangers have met opening day, along with 2013 and 2018. Houston would then play its first road series in Atlanta and Boston.

The Astros are scheduled for four off-days in the first 19 days of the season. They would not play more than nine days in a row until a stretch of 13 in a row from April 30 to May 12.

Their first three-city road trip would occur June 4-13, with series at Tampa Bay, Pittsburgh and Detroit. They have one other Aug. 20-29 at Milwaukee, Chicago and Seattle.

The Rangers, Red Sox, Guardians, Blue Jays, Yankees and Angels are all scheduled to visit Daikin Park before the end of April. Houston would host the Yankees for a three-game set April 23-25.

The Astros would also visit Yankee Stadium over Fourth of July weekend, for a three-game series July 2-4. They would play at home Memorial Day, against the Mariners, and on the road Labor Day, in St. Louis.

National League teams set to visit Daikin Park are the Nationals (May 7-9), Cubs (May 14-16), Reds (July 6-8), Giants (July 9-11), Rockies (July 23-25), Padres (July 30-Aug. 1), Mets (Aug. 17-19) and Phillies (Sept. 17-19).

Houston has two three-series homestands, both after the All-Star break. It would host the Rockies, Tigers and Padres from July 23-Aug. 1, then the Orioles, Twins and Mets from Aug. 10-19.

The Astros are scheduled to finish the season on the road with series against the Athletics and Angels.

In 2022, a lockout resulted in MLB postponing opening day from March 31 to April 7, though a full 162-game season was played. There is widespread belief that another lockout could occur when the current collective bargaining agreement between MLB and the MLB Players Association expires on Dec. 1.