UPDATE (6:30P) – As of 6:30 p.m., the northbound main lanes of US 281 have been reopened to traffic. The incident remains under investigation.

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SAN ANTONIO – Emergency crews responded to a major multi-vehicle incident on the Northbound lanes of US 281.

Around 3:20 pm on Saturday, first responders were called to the scene of a multi-vehicle incident along US 281 near Bitters Road on the North Side.

The incident resulted in the closure of all northbound lanes as crews worked to clear the scene.

This is a developing story.