March 6, 2026, 11:16 a.m. ET

The LA Clippers (30-31) and San Antonio Spurs (45-17) meet Friday at Frost Bank Center in San Antonio, Texas, at 9:30 p.m. ET (ESPN). Let’s analyze BetMGM Sportsbook’s NBA odds around the Clippers vs. Spurs and make our expert NBA picks and predictions for the best bets.

2024-25 season series: Clippers won 3-1

In their final head-to-head meeting last season on April 8, 2025, the Clippers won 122-117 despite being 12.5-point home underdogs. The Over (229.0) cashed as a trio of Clippers went for more than 20 points — G Norman Powell (25), C Ivica Zubac (24) and G James Harden (21). None of those three are still with LA.

The Clippers are coming off a 130-107 home win over the Indiana Pacers on Wednesday, covering the 11.5-point spread. F Kawhi Leonard scored a team-high 29 points with the Over (229.5) cashing.

The Spurs got a 121-106 home win over the Detroit Pistons on Thursday, easily covering the 3-point spread. C Victor Wembanyama led San Antonio with 38 points and 16 rebounds as the Under (229.5) hit.

Watch the NBA on Fubo!Clippers at Spurs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 11:05 a.m. ET.

Moneyline (ML): Clippers +230 (bet $100 to win $230) | Spurs -295 (bet $295 to win $100)Against the spread (ATS): Clippers +7.5 (-118) | Spurs -7.5 (-102)Over/Under (O/U): 222.5 (O: -110 | U: -110)Clippers at Spurs key injuries

Clippers

G Darius Garland (toe) outC Yanic Konan Niederhauser (foot) outF John Collins (neck) out

Spurs

(Not yet submitted — below was for Thursday’s game)

C Mason Plumlee (reconditioning) outF Harrison Barnes (ankle) out

For most recent updates: Official NBA injury report.

Clippers at Spurs picks and predictionsPrediction

Spurs 114, Clippers 104

AVOID.

Although I like the Spurs to win comfortably, the payout on the ML still isn’t worth the risk. Betting them to cover the spread is much safer and more logical.

BET SPURS -7.5 (-102).

The Spurs are one of the hottest teams in the NBA, winners of 13 of their last 14 games. They are 10-3-1 ATS in that span and each of their last 3 wins have been by double digits. To the Clippers’ credit, they are 9-1 ATS over their last 10 games but haven’t played the greatest competition.

BET UNDER 222.5 (-110).

The Spurs have hit the Under in 5 of their last 6 games. The Clippers are 5-5 Over/Under over their last 10 games and rank in the bottom third of the league in points per game at 112.4.

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