Two Houston men have been sentenced to over 25 years in federal prison for roles in a multi-state drug trafficking and burglary ring, prosecutors say.

HOUSTON — Two Houston men have been sentenced to more than 25 years combined in federal prison after investigators say they were part of a criminal organization responsible for dozens of pharmacy burglaries across multiple states and millions of dollars in stolen drugs.

Federal prosecutors say the group stole large quantities of controlled substances from pharmacies around the country and distributed them illegally. The sentencing marks another step in a sweeping federal case targeting the multi-state burglary ring.


Houston men receive federal prison sentences

According to the U.S. Attorney’s Office for the Eastern District of Arkansas, Antoinen Dion Hampton, 39, and Reginald Tremayne Jackson, 35, were sentenced Thursday by U.S. District Judge Brian S. Miller.

Together, the two men received 308 months in federal prison.

Hampton was sentenced to 188 months for conspiracy to distribute and possess with intent to distribute controlled substances — including oxycodone, hydrocodone and alprazolam — and for conspiracy to commit money laundering.

Jackson was sentenced to 120 months for conspiracy to distribute and possess with intent to distribute controlled substances.

Both men will also serve three years of supervised release after their prison sentences. Federal officials said restitution will be determined later.


Investigation uncovered widespread pharmacy burglaries

Investigators say Hampton and Jackson were part of a drug trafficking organization that included documented gang members from the Fifth Ward area.

Authorities say the group stole more than 96,000 tablets of Schedule II controlled substances, including oxycodone, hydrocodone and Adderall, from pharmacies across the United States.

The burglaries occurred in multiple states, including:

ArkansasOklahomaKansasGeorgiaFlorida

According to investigators, the street value of drugs stolen in Arkansas burglaries alone was nearly $1.6 million. Overall, authorities estimate the organization distributed controlled substances worth more than $12 million.

During the investigation, law enforcement also seized:

Six firearmsAbout $79,000 in cashCustom jewelry valued at approximately $330,000


Criminal histories detailed in court filings

Prosecutors said Hampton had an extensive criminal history that included felony convictions for burglary-related offenses. Investigators say he participated in more than 50 pharmacy burglaries across the United States, including crimes in states such as Tennessee, Colorado, Utah, Michigan, Virginia and Wyoming.

Jackson, who had already been serving a 36-month federal sentence in Missouri at the time of his arrest, was classified as a career offender because of prior violent felony or serious drug convictions.

Authorities say Jackson participated in 10 pharmacy burglaries in Arkansas and Oklahoma.


Other members of the burglary ring also sentenced

Federal prosecutors said the pharmacy burglary ring involved numerous defendants.

Keith Wayne Brown, 36, of Humble, who authorities identified as the leader of the organization, previously pleaded guilty and was sentenced in January 2025 to 209 months — more than 17 years — in federal prison.

Another Houston-area defendant, Alexis Simone Garner, 33, was sentenced in April 2025 to one year and one day in federal prison for conspiracy to commit money laundering.


Multi-agency investigation

The investigation involved numerous federal, state and local law enforcement agencies.

Those agencies included the DEA, FBI, U.S. Marshals Service, Arkansas State Police, Harris County Sheriff’s Office and Houston Police Department, along with several DEA regional offices across the country.

Federal prosecutors in Arkansas are handling the case as part of the Homeland Security Task Force initiative, which focuses on targeting criminal organizations involved in drug trafficking and other serious crimes.

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