The Houston Cougars (6-1, 3-1 Big 12) visit the No. 25 Arizona State Sun Devils (5-2, 3-1) Saturday in Tempe, Arizona. Kickoff from Mountain America Stadium is at 8 p.m. ET (ESPN2). Let’s analyze BetMGM Sportsbook’s NCAA football odds around the Houston vs. Arizona State odds and make our expert college football picks and predictions for the best bets.

Houston has won 2 straight games and is coming off a 31-28 home win over Arizona as 2-point underdogs, with the Over (47) cashing. The Cougars rushed for 232 yards and, after allowing Arizona to tie the game after leading 28-14 in the second half, K Ethan Sanchez made a 41-yard field goal as time expired.

The Sun Devils are coming off an upset at home over previously No. 7 Texas Tech with a 26-22 win as 7.5-point underdogs, with the Under (52.5) cashing. After giving up a 19-7 lead to trail 22-19, RB Raleek Brown had a 1-yard touchdown run with 34 seconds left. WR Jordyn Tyson had 10 catches for 105 yards and a touchdown.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:50 p.m. ET.

Moneyline (ML): Houston +225 (bet $100 to win $225) | Arizona State -285 (bet $285 to win $100)Against the spread (ATS): Houston +7 (-110) | Arizona State -7 (-110)Over/Under (O/U): 46.5 (O: -115 | U: -105)Houston at Arizona State picks and predictionsPrediction

Arizona State 27, Houston 23

The Devils will be missing Tyson, who is out with a hamstring injury. He’s not only is ASU’s leading receiver and scorer, he leads the conference in receptions, receiving yards and touchdowns. But ASU played without him in the Big 12 Championship and the College Football Playoff and still played well.

Houston rushed for 232 yards last week, but Arizona State held Texas Tech to 110 yards on the ground after the Red Raiders piled up 372 yards the week before. It also held Texas Tech to 22 points after they had scored no fewer than 34 previously.

ASU has not lost in Tempe since 2023.

Expect the Sun Devils to win, but the ML odds don’t give you the value you will want.

PASS.

The Devils have not won a conference game by more than 4 points this season. They have played all 3 of their conference games down to the wire.

Houston’s only loss was a 24-point defeat.

BET HOUSTON +7 (-110).

Houston hasn’t scored fewer than 27 points in their 6 wins, but excluding the loss in Utah, Arizona State hasn’t allowed more than 24.

Arizona State’s last 5 games have surpassed 46 points.

Four of the last 5 for Houston have surpassed 46 points.

BET OVER 46.5 (-115).

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