April 26, 2026, 10:44 a.m. ET

The No. 2 San Antonio Spurs visit the No. 7 Portland Trail Blazers Sunday in Game 4 of the best-of-7 first-round NBA playoff series. Tip-off from Moda Center in Portland, Oregon, is at 3:30 p.m. ET (ESPN). Let’s analyze NBA odds around the Spurs vs. Trail Blazers odds and make our expert NBA picks and predictions for the best bets.

Best-of-7 series: Spurs lead 2-1

After losing Game 2 106-103 in San Antonio when C Victor Wembanyama exited with a concussion, the Spurs took back the series lead Friday in Game 3, winning 120-108 in Portland as 1.5-point spread favorites with the Over (219.5) cashing. Wembanyama missed the game, but G Stephon Castle stepped up with 33 points, and G Dylan Harper came off the bench for 27.

The Blazers shot 41 percent from the field. They had as much as a 15-point lead, but were outscored by 18 points in the second half. G Jrue Holiday led Portland with 29 points, making 5 of 9 from 3.

Watch the NBA on Fubo!Spurs at Trail Blazers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:33 a.m. ET.

Moneyline (ML): Spurs -210 (bet $210 to win $100) | Trail Blazers +170 (bet $100 to win $170)Against the spread (ATS): Spurs -5.5 (-105) | Trail Blazers +5.5 (-115)Over/Under (O/U): 218.5 (O: -110 | U: -110)Spurs at Trail Blazers key injuries

Spurs

G Jordan McLaughlin (ankle) questionableC Victor Wembanyama (concussion) questionable

Trail Blazers

G Damian Lillard (Achilles) out

For most recent updates: Official NBA injury report.

Spurs at Trail Blazers picks and predictionsPrediction

Spurs 111, Trail Blazers 100

The Spurs made their adjustments without Wemby in the lineup and found their groove in the second half of Game 3. Including the postseason, the Spurs are now 30-12 in away games. They have held the Blazers to an average of 103.7 points per game in 6 meetings between the regular season and this series.

The Blazers had their chance to take control of the series in Game 3. They are going to see this series slip away.

The Spurs take a 3-1 lead, but the spread is the better bet.

PASS.

All 4 of the Spurs’ wins over the Blazers this year have been by double digits.

The Blazers are 1-6 ATS in their last 7 outright losses.

The Spurs have covered the spread in their last 6 outright wins.

BET SPURS -5.5 (-105).

The Under cashed in the first 2 games of the series, and in all 3 regular-season matchups. But the Over hit in Game 3, as the Spurs’ offense pace picked up.

The Blazers scored only 43 second-half points in Game 3.

BET UNDER 218.5 (-110).

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