May 14, 2026, 11:47 p.m. ET
The San Antonio Spurs and Minnesota Timberwolves meet Friday in Game 6 of their second-round Western Conference playoff series. Tip from Target Center in Minneapolis, Minnesota, is set for 9:30 p.m. ET (Prime Video). Let’s analyze NBA odds around the Spurs vs. Timberwolves odds and make our expert NBA picks and predictions for the best bets.
Playoff series: Spurs lead 3-2
The Spurs beat the Timberwolves 126-97 in Game 5 Tuesday to pull ahead in the series. They covered as a 10.5-point home favorite with the Over (217.5) cashing. Spurs C Victor Wembanyama, who was ejected in Game 4 for a flagrant foul, finished with 27 points and 17 rebounds. F Keldon Johnson scored 21 points off the bench, hitting 8 of 11 shots.
The Timberwolves are led by G Anthony Edwards, who scored 32 and 36 points in Game 3 and 4, scored just 20 points in Game 5 despite playing 39 minutes. F Julius Randle had 17 points and 10 rebounds. The Timberwolves hit just 9 of 33 3-point attempts (27%).
Watch the NBA on Fubo!Spurs at Timberwolves odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 11:23 p.m. ET.
Moneyline (ML): Spurs -210 (bet $210 to win $100) | Timberwolves +170 (bet $100 to win $170)Against the spread (ATS): Spurs -5.5 (-105) | Timberwolves +5.5 (-115)Over/Under (O/U): 218.5 (O: -110 | U: -110)Spurs at Timberwolves key injuries
Spurs
None
Timberwolves
G Donte DiVincenzo (achilles) out
For most recent updates: Official NBA injury report.
Spurs at Timberwolves picks and predictionsPrediction
Timberwolves 113, Spurs 109
PASS.
The Timberwolves (+170) have solid value to win outright at home and push this series to a Game 7. However, the margin on the spread here and the odds there make that the more enticing play to me.
BET TIMBERWOLVES +5.5 (-115).
The Spurs are a talented side, but they are still young and mostly haven’t had to win high-intensity games. San Antonio scored 115 and 109 points in the 2 games in Minnesota this series.
Edwards has too much pride to let his team bow out on their home court. The Wolves offense has also competed at a much higher level at home, scoring sub-105 points in all 3 away games in the series yet tallying at least 108 in each game at Target Center. Minnesota is 3-1 straight up and ATS following defeats in the playoffs.
Expect Antman to get things going once again and extend the series, while also covering the spread for Minnesota. You might even consider Edwards +30 points (+155).
BET OVER 218.5 (-110).
The Over has hit in 4 straight games. The Timberwolves have scored at least 108 points in all 5 home games in the playoffs.
Meanwhile, the Spurs are on fire offensively, scoring at least 115 points in 3 of their last 4 games. San Antonio is 3-1 O/U on the road in the postseason.
During the regular season, the Spurs had the third-highest scoring average (119.8) with the Timberwolves seventh (118.0)
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