The San Antonio Spurs (11-5) and Portland Trail Blazers (8-10) meet Wednesday at Moda Center in Portland, Oregon, for an NBA Cup game. Tip-off is scheduled for 10 p.m. ET. Let’s analyze BetMGM Sportsbook’s NBA odds around the Spurs vs. Trail Blazers odds and make our expert NBA picks and predictions for the best bets.

2024-25 season series: Spurs won 3-1

The Spurs were tripped up 111-102 Sunday, halting a 3-game win and cover streak. G De’Aaron Fox had 26 points, while F Julian Champagnie chipped in with 10 points and 12 rebounds for a double-double. The Under (234) cashed, and it is now 4-1 in the past 5 games.

The Trail Blazers posted a 115-103 victory as 1-point underdogs Monday as the Under (231) cashed. F Jerami Grant rolled up 35 points with 4 rebounds, 4 assists and a block with 3 triples. Portland has picked up 2 wins in the past 3 games, while going 3-1 against the spread (ATS) in the past 4 outings. The Under is 3-1 in the past 4 games, too.

Watch the NBA on Fubo!Spurs at Trail Blazers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:32 a.m. ET.

Moneyline (ML): Spurs +100 (bet $100 to win $100) | Trail Blazers -120 (bet $120 to win $100)Against the spread: Spurs +1.5 (-110) | Trail Blazers -1.5 (-110)Over/Under (O/U): 239.5 (O: -105 | U: -115)Spurs at Trail Blazers injuries

Spurs

G Stephon Castle (hip) outG Dylan Harper (calf) questionableG Jordan McLaughlin (hamstring) outC Victor Wembanyama (calf) out

Trail Blazers

G Scoot Henderson (hamstring) outG Jrue Holiday (calf) outG Damian Lillard (Achilles) outG Shaedon Sharpe (calf) questionableG Matisse Thybulle (thumb) outG Blake Wesley (foot) out

For most recent updates: Official NBA injury report.

Spurs at Trail Blazers picks and predictionsPrediction

Spurs 113, Trail Blazers 107

The SPURS (+100) are worth playing at even money, even with Wembanyama on the shelf. San Antonio has won 3 of its past 4 games, and defensively, it has been stout with or without Wemby in the middle.

The Blazers have picked up 2 victories in their past 3 games, but those are their only wins in the past 7 outings. Since Nov. 8 in Miami, Portland has won just 3 of 10 games.

Spurs +1.5 (-110) makes little sense to play over the moneyline unless you are absolutely convinced Portland will win — but only by a single point.

PASS, and just look to the moneyline instead.

The UNDER 239.5 (-115) is the best play on the board.

The Under is 3-1 in Portland’s past 4 games and 4-1 in San Antonio’s past 5 outings. With the Spurs missing their big man — and the offense that comes with him — along with a lengthy injury list for the Blazers, it’s wise to go low on the total.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow @danieledobish on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Access more NBA coverage:

HoopsHype | Celtics Wire | Nets Wire | Rockets Wire | Sixers Wire | Thunder Wire | Warriors Wire | LeBron Wire | Rookie Wire | List Wire

Our team of savvy editors independently handpicks all recommendations. If you purchase through our links, the USA Today Network may earn a commission. Prices were accurate at the time of publication but may change.

Gambling involves risk. Please only gamble with funds that you can comfortably afford to lose.  While we do our utmost to offer good advice and information we cannot be held responsible for any loss that may be incurred as a result of gambling.  We do our best to make sure all the information that we provide on this site is correct. However, from time to time mistakes will be made and we will not be held liable. Please check any stats or information if you are unsure how accurate they are. No guarantees are made with regards to results or financial gain. All forms of betting carry financial risk and it is up to the individual to make bets with or without the assistance of information provided on this site and we cannot be held responsible for any loss that may be incurred as a result of following the betting tips provided on this site.  Past performances do not guarantee success in the future and betting odds fluctuate from one minute to the next. The material contained on this site is intended to inform, entertain and educate the reader and in no way represents an inducement to gamble legally or illegally or any sort of professional advice.

Gannett may earn revenue from sports betting operators for audience referrals to betting services. Sports betting operators have no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. Terms apply, see operator site for Terms and Conditions. If you or someone you know has a gambling problem, help is available. Call the National Council on Problem Gambling 24/7 at 1-800-GAMBLER (NJ, OH), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA), 1-800-9-WITH-IT (IN). Must be 21 or older to gamble. Sports betting and gambling are not legal in all locations. Be sure to comply with laws applicable where you reside. It is your sole responsibility to act in accordance with your local laws.